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Estrogen-dependent downregulation of hypoxia-inducible factor (HIF)-2α in invasive breast cancer cells

The involvement of estrogen (E2) and hypoxia in tumor progression is well established. Hypoxia has been reported to activate and degrade estrogen receptor alpha (ERα) in breast cancer cells. Furthermore, E2 has been shown to regulate hypoxia-inducible factor (HIF)-1α protein, but its role in HIF-2α...

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Detalles Bibliográficos
Autores principales:	Fuady, Jerry H., Gutsche, Katrin, Santambrogio, Sara, Varga, Zsuzsanna, Hoogewijs, David, Wenger, Roland H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058746/ https://www.ncbi.nlm.nih.gov/pubmed/27105516 http://dx.doi.org/10.18632/oncotarget.8866

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