TET1 inhibits gastric cancer growth and metastasis by PTEN demethylation and re-expression

Ten-Eleven Translocation 1 (TET1) is a member of ten eleven translocation enzymes, which convert 5-methylcytosine (5-mC) to 5-hydroxymethylcytosine (5-hmC). TET1 can promote CpG islands demethylation in specific genes and often absent in various cancers. Herein, we found that TET1 expression and 5-h...

Descripción completa

Detalles Bibliográficos
Autores principales: Pei, Yao-fei, Tao, Ran, Li, Jian-fang, Su, Li-ping, Yu, Bei-qin, Wu, Xiong-yan, Yan, Min, Gu, Qin-long, Zhu, Zheng-gang, Liu, Bing-ya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058759/
https://www.ncbi.nlm.nih.gov/pubmed/27121319
http://dx.doi.org/10.18632/oncotarget.8900

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058759/
https://www.ncbi.nlm.nih.gov/pubmed/27121319
http://dx.doi.org/10.18632/oncotarget.8900

Ejemplares similares