Cargando…

TET1 inhibits gastric cancer growth and metastasis by PTEN demethylation and re-expression

Ten-Eleven Translocation 1 (TET1) is a member of ten eleven translocation enzymes, which convert 5-methylcytosine (5-mC) to 5-hydroxymethylcytosine (5-hmC). TET1 can promote CpG islands demethylation in specific genes and often absent in various cancers. Herein, we found that TET1 expression and 5-h...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pei, Yao-fei, Tao, Ran, Li, Jian-fang, Su, Li-ping, Yu, Bei-qin, Wu, Xiong-yan, Yan, Min, Gu, Qin-long, Zhu, Zheng-gang, Liu, Bing-ya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058759/ https://www.ncbi.nlm.nih.gov/pubmed/27121319 http://dx.doi.org/10.18632/oncotarget.8900

Ejemplares similares

microRNA-21 promotes tumor proliferation and invasion in gastric cancer by targeting PTEN
por: ZHANG, BAO GUI, et al.
Publicado: (2012)

Controlled re-activation of epigenetically silenced Tet promoter-driven transgene expression by targeted demethylation
por: Gödecke, Natascha, et al.
Publicado: (2017)

TET proteins and the control of cytosine demethylation in cancer
por: Scourzic, Laurianne, et al.
Publicado: (2015)

Association study between SNP rs150689919 in the DNA demethylation gene, TET1, and Parkinson’s disease in Chinese Han population
por: Liao, Xin-xin, et al.
Publicado: (2013)

TET family dioxygenases and DNA demethylation in stem cells and cancers
por: An, Jungeun, et al.
Publicado: (2017)

TET2 coactivates gene expression through demethylation of enhancers
por: Wang, Lu, et al.
Publicado: (2018)

Loss of TET reprograms Wnt signaling through impaired demethylation to promote lung cancer development
por: Xu, Qin, et al.
Publicado: (2022)

Inhibition of Tet1- and Tet2-mediated DNA demethylation promotes immunomodulation of periodontal ligament stem cells
por: Yu, Tingting, et al.
Publicado: (2019)

Tet-mediated DNA demethylation regulates specification of hematopoietic stem and progenitor cells during mammalian embryogenesis
por: Ma, Liyang, et al.
Publicado: (2022)

Roles of TET and TDG in DNA demethylation in proliferating and non-proliferating immune cells
por: Onodera, Atsushi, et al.
Publicado: (2021)

Vitamin C boosts DNA demethylation in TET2 germline mutation carriers
por: Taira, Aurora, et al.
Publicado: (2023)

ETV2-TET1/TET2 Complexes Induce Endothelial Cell-Specific Robo4 Expression via Promoter Demethylation
por: Tanaka, Toru, et al.
Publicado: (2018)

Tet1 and Tet2 maintain mesenchymal stem cell homeostasis via demethylation of the P2rX7 promoter
por: Yang, Ruili, et al.
Publicado: (2018)

Hemi-methylated CpG sites connect Dnmt1-knockdown-induced and Tet1-induced DNA demethylation during somatic cell reprogramming
por: He, Songwei, et al.
Publicado: (2019)

Targeted DNA demethylation of the Arabidopsis genome using the human TET1 catalytic domain
por: Gallego-Bartolomé, Javier, et al.
Publicado: (2018)

Transcription Factors Drive Tet2-Mediated Enhancer Demethylation to Reprogram Cell Fate
por: Sardina, Jose Luis, et al.
Publicado: (2018)

TET2 catalyzes active DNA demethylation of the Sry promoter and enhances its expression
por: Okashita, Naoki, et al.
Publicado: (2019)

TET1 regulates gene expression and repression of endogenous retroviruses independent of DNA demethylation
por: Stolz, Paul, et al.
Publicado: (2022)

Recent evolution of a TET-controlled and DPPA3/STELLA-driven pathway of passive DNA demethylation in mammals
por: Mulholland, Christopher B., et al.
Publicado: (2020)

Targeted DNA Demethylation and Endogenous Gene Activation Using Programmable TALE-TET1 Fusions
por: Maeder, Morgan L, et al.
Publicado: (2013)

Tet1-mediated DNA demethylation regulates neuronal cell death induced by oxidative stress
por: Xin, Yong-Juan, et al.
Publicado: (2015)

Improvement of Foxp3 stability through CNS2 demethylation by TET enzyme induction and activation
por: Someya, Kazue, et al.
Publicado: (2017)

DNA Methylation and Demethylation Are Regulated by Functional DNA Methyltransferases and DnTET Enzymes in Diuraphis noxia
por: du Preez, Pieter H., et al.
Publicado: (2020)

TET2-interacting long noncoding RNA promotes active DNA demethylation of the MMP-9 promoter in diabetic wound healing
por: Zhou, Liyan, et al.
Publicado: (2019)

LncRNA TUG1 Demethylated by TET2 Promotes NLRP3 Expression, Contributes to Cerebral Ischemia/Reperfusion Inflammatory Injury
por: Yin, Min, et al.
Publicado: (2021)

Vitamin C induces Tet-dependent DNA demethylation in ESCs to promote a blastocyst-like state
por: Blaschke, Kathryn, et al.
Publicado: (2013)

Genome-wide Bisulfite Sequencing in Zygotes Identifies Demethylation Targets and Maps the Contribution of TET3 Oxidation
por: Peat, Julian R., et al.
Publicado: (2014)

ERRATUM: Tet1-mediated DNA demethylation regulates neuronal cell death induced by oxidative stress
por: Xin, Yong-Juan, et al.
Publicado: (2015)

TET3‐mediated demethylation in tomato activates expression of a CETS gene that stimulates vegetative growth
por: Hollwey, Elizabeth, et al.
Publicado: (2017)

High salt promotes autoimmunity by TET2-induced DNA demethylation and driving the differentiation of Tfh cells
por: Wu, Haijing, et al.
Publicado: (2016)

Tet Proteins Regulate Neutrophil Granulation in Zebrafish through Demethylation of socs3b mRNA
por: Banks, Kelly M., et al.
Publicado: (2021)

Author Correction: Recent evolution of a TET-controlled and DPPA3/STELLA-driven pathway of passive DNA demethylation in mammals
por: Mulholland, Christopher B., et al.
Publicado: (2020)

Loss and reduced expression of PTEN correlate with advanced-stage gastric carcinoma
por: ZHU, XUEHUA, et al.
Publicado: (2013)

CRISPR-dCas9 mediated TET1 targeting for selective DNA demethylation at BRCA1 promoter
por: Choudhury, Samrat Roy, et al.
Publicado: (2016)

Proinflammatory cytokines promote TET2-mediated DNA demethylation during CD8 T cell effector differentiation
por: Zebley, Caitlin C., et al.
Publicado: (2021)

DNA demethylation in the PTEN gene promoter induced by 5-azacytidine activates PTEN expression in the MG-63 human osteosarcoma cell line
por: SONG, DEYE, et al.
Publicado: (2014)

AIF inhibits tumor metastasis by protecting PTEN from oxidation
por: Shen, Shao-Ming, et al.
Publicado: (2015)

Systemic Deficiency of PTEN Accelerates Breast Cancer Growth and Metastasis
por: Chen, Jing, et al.
Publicado: (2022)

Epigenetic modification of Nrf2 in 5-fluorouracil-resistant colon cancer cells: involvement of TET-dependent DNA demethylation
por: Kang, K A, et al.
Publicado: (2014)

Biochemical reconstitution of TET1–TDG–BER-dependent active DNA demethylation reveals a highly coordinated mechanism
por: Weber, Alain R., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_st83i2sh5s04c625jhhakfnkn1