Cargando…
CYB5R1 links epithelial-mesenchymal transition and poor prognosis in colorectal cancer
Colorectal cancers show significant tumor cell heterogeneity within the same core genetic background. Epithelial-mesenchymal transition (EMT) is an important functional aspect of this heterogeneity and hallmark of colorectal cancer progression. Here, we identify CYB5R1, an enzyme involved in oxidati...
Autores principales: | Woischke, Christine, Blaj, Cristina, Schmidt, Eva Marina, Lamprecht, Sebastian, Engel, Jutta, Hermeking, Heiko, Kirchner, Thomas, Horst, David |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058761/ https://www.ncbi.nlm.nih.gov/pubmed/27120783 http://dx.doi.org/10.18632/oncotarget.8912 |
Ejemplares similares
-
Multicolor lineage tracing reveals clonal architecture and dynamics in colon cancer
por: Lamprecht, Sebastian, et al.
Publicado: (2017) -
Colorectal Cancers Mimic Structural Organization of Normal Colonic Crypts
por: Cernat, Laura, et al.
Publicado: (2014) -
Targeting tumor cell plasticity by combined inhibition of NOTCH and MAPK signaling in colon cancer
por: Schmidt, Eva Marina, et al.
Publicado: (2018) -
AP4 is a mediator of epithelial–mesenchymal transition and metastasis in colorectal cancer
por: Jackstadt, Rene, et al.
Publicado: (2013) -
p53 directly activates cystatin D/CST5 to mediate mesenchymal-epithelial transition: a possible link to tumor suppression by vitamin D3
por: Hünten, Sabine, et al.
Publicado: (2015)