CUL2 overexpression driven by CUL2/E2F1/miR-424 regulatory loop promotes HPV16 E7 induced cervical carcinogenesis

It has been shown that HPV16 E7, but not other genotypes, can bind to scaffold protein CUL2 during inducing cervical carcinogenesis, but the expression level, associated regulating mechanism, and potential carcinogenicity of CUL2 itself is still unknown as yet. Here, we demonstrated that CUL2 was sp...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Junfen, Fang, Yifeng, Wang, Xinyu, Wang, Fenfen, Tian, Qifang, Li, Ying, Xie, Xing, Cheng, Xiaodong, Lu, Weiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058775/
https://www.ncbi.nlm.nih.gov/pubmed/27153550
http://dx.doi.org/10.18632/oncotarget.9127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058775/
https://www.ncbi.nlm.nih.gov/pubmed/27153550
http://dx.doi.org/10.18632/oncotarget.9127

Ejemplares similares