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Giant tubular adenoma with malignancy clinical characteristics in a female teenager: Case report and a review of the literature
BACKGROUND: Adenomas of the colon are usually benign tumors which carry a tendency for malignancy. These tumors can be villous, tubular, tubulovillous, or sessile serrated. Those with adenomatous structure can develop malignant characteristics in 1.5% to 9.4% of cases. METHODS: We present a case rep...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059034/ https://www.ncbi.nlm.nih.gov/pubmed/27749532 http://dx.doi.org/10.1097/MD.0000000000004805 |
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author | Mărginean, Cristina Oana Mărginean, Maria Oana Simu, Iunius Horvath, Adrienne Meliţ, Lorena Elena |
author_facet | Mărginean, Cristina Oana Mărginean, Maria Oana Simu, Iunius Horvath, Adrienne Meliţ, Lorena Elena |
author_sort | Mărginean, Cristina Oana |
collection | PubMed |
description | BACKGROUND: Adenomas of the colon are usually benign tumors which carry a tendency for malignancy. These tumors can be villous, tubular, tubulovillous, or sessile serrated. Those with adenomatous structure can develop malignant characteristics in 1.5% to 9.4% of cases. METHODS: We present a case report of a 16-year-old female adolescent with an adenoma of the descending colon. History revealed prolonged diarrheic syndrome for the past 6 months, repeated headache, and a weight loss of ∼5 kg in the past month. One week before the admission, the patient presented an episode of inferior digestive hemorrhage. RESULTS: On admission laboratory tests revealed iron deficiency anemia, and a mildly increased erythrocyte sedimentation rate. The abdominal ultrasound revealed an inhomogeneous mass of the descending colon and 2 hyperechoic lesions in the liver. The colonoscopy showed a tumor of the descending colon, a tubular adenoma according to the pathological examination. Additionally, we noted an atypical presentation of the tumor and the signs of mild dysplasia identified at the pathological examination. CONCLUSION: Weight loss, bowel transit alterations, loss of appetite, and inferior hemorrhage in an adolescent can be symptoms of a benign or malignant tumor of the colon. |
format | Online Article Text |
id | pubmed-5059034 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-50590342016-11-01 Giant tubular adenoma with malignancy clinical characteristics in a female teenager: Case report and a review of the literature Mărginean, Cristina Oana Mărginean, Maria Oana Simu, Iunius Horvath, Adrienne Meliţ, Lorena Elena Medicine (Baltimore) 6200 BACKGROUND: Adenomas of the colon are usually benign tumors which carry a tendency for malignancy. These tumors can be villous, tubular, tubulovillous, or sessile serrated. Those with adenomatous structure can develop malignant characteristics in 1.5% to 9.4% of cases. METHODS: We present a case report of a 16-year-old female adolescent with an adenoma of the descending colon. History revealed prolonged diarrheic syndrome for the past 6 months, repeated headache, and a weight loss of ∼5 kg in the past month. One week before the admission, the patient presented an episode of inferior digestive hemorrhage. RESULTS: On admission laboratory tests revealed iron deficiency anemia, and a mildly increased erythrocyte sedimentation rate. The abdominal ultrasound revealed an inhomogeneous mass of the descending colon and 2 hyperechoic lesions in the liver. The colonoscopy showed a tumor of the descending colon, a tubular adenoma according to the pathological examination. Additionally, we noted an atypical presentation of the tumor and the signs of mild dysplasia identified at the pathological examination. CONCLUSION: Weight loss, bowel transit alterations, loss of appetite, and inferior hemorrhage in an adolescent can be symptoms of a benign or malignant tumor of the colon. Wolters Kluwer Health 2016-10-07 /pmc/articles/PMC5059034/ /pubmed/27749532 http://dx.doi.org/10.1097/MD.0000000000004805 Text en Copyright © 2016 the Author(s). Published by Wolters Kluwer Health, Inc. All rights reserved. http://creativecommons.org/licenses/by-nc-nd/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0, where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0 |
spellingShingle | 6200 Mărginean, Cristina Oana Mărginean, Maria Oana Simu, Iunius Horvath, Adrienne Meliţ, Lorena Elena Giant tubular adenoma with malignancy clinical characteristics in a female teenager: Case report and a review of the literature |
title | Giant tubular adenoma with malignancy clinical characteristics in a female teenager: Case report and a review of the literature |
title_full | Giant tubular adenoma with malignancy clinical characteristics in a female teenager: Case report and a review of the literature |
title_fullStr | Giant tubular adenoma with malignancy clinical characteristics in a female teenager: Case report and a review of the literature |
title_full_unstemmed | Giant tubular adenoma with malignancy clinical characteristics in a female teenager: Case report and a review of the literature |
title_short | Giant tubular adenoma with malignancy clinical characteristics in a female teenager: Case report and a review of the literature |
title_sort | giant tubular adenoma with malignancy clinical characteristics in a female teenager: case report and a review of the literature |
topic | 6200 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059034/ https://www.ncbi.nlm.nih.gov/pubmed/27749532 http://dx.doi.org/10.1097/MD.0000000000004805 |
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