Calcium handling precedes cardiac differentiation to initiate the first heartbeat

The mammalian heartbeat is thought to begin just prior to the linear heart tube stage of development. How the initial contractions are established and the downstream consequences of the earliest contractile function on cardiac differentiation and morphogenesis have not been described. Using high-res...

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Detalles Bibliográficos
Autores principales: Tyser, Richard CV, Miranda, Antonio MA, Chen, Chiann-mun, Davidson, Sean M, Srinivas, Shankar, Riley, Paul R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Developmental Biology and Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059139/
https://www.ncbi.nlm.nih.gov/pubmed/27725084
http://dx.doi.org/10.7554/eLife.17113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059139/
https://www.ncbi.nlm.nih.gov/pubmed/27725084
http://dx.doi.org/10.7554/eLife.17113

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