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Functional validation of tensin2 SH2-PTB domain by CRISPR/Cas9-mediated genome editing

Podocytes are terminally differentiated and highly specialized cells in the glomerulus, and they form a crucial component of the glomerular filtration barrier. The ICGN mouse is a model of glomerular dysfunction that shows gross morphological changes in the podocyte foot process, accompanied by prot...

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Detalles Bibliográficos
Autores principales: MARUSUGI, Kiyoma, NAKANO, Kenta, SASAKI, Hayato, KIMURA, Junpei, YANOBU-TAKANASHI, Rieko, OKAMURA, Tadashi, SASAKI, Nobuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059368/
https://www.ncbi.nlm.nih.gov/pubmed/27246398
http://dx.doi.org/10.1292/jvms.16-0205