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Functional validation of tensin2 SH2-PTB domain by CRISPR/Cas9-mediated genome editing
Podocytes are terminally differentiated and highly specialized cells in the glomerulus, and they form a crucial component of the glomerular filtration barrier. The ICGN mouse is a model of glomerular dysfunction that shows gross morphological changes in the podocyte foot process, accompanied by prot...
Autores principales: | MARUSUGI, Kiyoma, NAKANO, Kenta, SASAKI, Hayato, KIMURA, Junpei, YANOBU-TAKANASHI, Rieko, OKAMURA, Tadashi, SASAKI, Nobuya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japanese Society of Veterinary Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059368/ https://www.ncbi.nlm.nih.gov/pubmed/27246398 http://dx.doi.org/10.1292/jvms.16-0205 |
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