Cargando…

Structure of ubiquitylated-Rpn10 provides insight into its autoregulation mechanism

Ubiquitin receptors decode ubiquitin signals into many cellular responses. Ubiquitin receptors also undergo coupled monoubiquitylation, and rapid deubiquitylation has hampered the characterization of the ubiquitylated state. Using bacteria that express a ubiquitylation apparatus, we purified and det...

Descripción completa

Detalles Bibliográficos
Autores principales:	Keren-Kaplan, Tal, Zeev Peters, Lee, Levin-Kravets, Olga, Attali, Ilan, Kleifeld, Oded, Shohat, Noa, Artzi, Shay, Zucker, Ori, Pilzer, Inbar, Reis, Noa, Glickman, Michael H., Ben-Aroya, Shay, Prag, Gali
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059453/ https://www.ncbi.nlm.nih.gov/pubmed/27698474 http://dx.doi.org/10.1038/ncomms12960

Ejemplares similares

Remodeling Membrane Binding by Mono-Ubiquitylation
por: Tanner, Neta, et al.
Publicado: (2019)

Dual function of Rpn5 in two PCI complexes, the 26S proteasome and COP9 signalosome
por: Yu, Zanlin, et al.
Publicado: (2011)

MPN+, a putative catalytic motif found in a subset of MPN domain proteins from eukaryotes and prokaryotes, is critical for Rpn11 function
por: Maytal-Kivity, Vered, et al.
Publicado: (2002)

A novel recognition site for polyubiquitin and ubiquitin-like signals in an unexpected region of proteasomal subunit Rpn1
por: Boughton, Andrew J., et al.
Publicado: (2021)

Ubiquitination and receptor-mediated mitophagy converge to eliminate oxidation-damaged mitochondria during hypoxia
por: Sulkshane, Prasad, et al.
Publicado: (2021)

The Protein Quality Control Machinery Regulates Its Misassembled Proteasome Subunits
por: Peters, Lee Zeev, et al.
Publicado: (2015)

Nonconformity in ubiquitin compliance
por: Ziv, Inbal, et al.
Publicado: (2009)

Formation and dissociation of proteasome storage granules are regulated by cytosolic pH
por: Peters, Lee Zeev, et al.
Publicado: (2013)

Spatial Organization of Proteasome Aggregates in the Regulation of Proteasome Homeostasis
por: Karmon, Ofri, et al.
Publicado: (2020)

Structure of the Rpn13-Rpn2 complex provides insights for Rpn13 and Uch37 as anticancer targets
por: Lu, Xiuxiu, et al.
Publicado: (2017)

Inactive Proteasomes Routed to Autophagic Turnover Are Confined within the Soluble Fraction of the Cell
por: Friedman, Keren, et al.
Publicado: (2022)

A comparison of the power of breathing sounds signals acquired with a smart stethoscope from a cohort of COVID-19 patients at peak disease, and pre-discharge from the hospital
por: Kasim, Nour, et al.
Publicado: (2022)

Coronaviral PLpro proteases and the immunomodulatory roles of conjugated versus free Interferon Stimulated Gene product-15 (ISG15)
por: Gold, Inbar Magid, et al.
Publicado: (2022)

The ups and downs of biological timers
por: Rappaport, Noa, et al.
Publicado: (2005)

The Hetero-Hexameric Nature of a Chloroplast AAA+ FtsH Protease Contributes to Its Thermodynamic Stability
por: Moldavski, Ofer, et al.
Publicado: (2012)

Structure of Rpn10 and Its Interactions with Polyubiquitin Chains and the Proteasome Subunit Rpn12
por: Riedinger, Christiane, et al.
Publicado: (2010)

Redundant Roles of Rpn10 and Rpn13 in Recognition of Ubiquitinated Proteins and Cellular Homeostasis
por: Hamazaki, Jun, et al.
Publicado: (2015)

Structural and functional characterization of Rpn12 identifies residues required for Rpn10 proteasome incorporation
por: Boehringer, Jonas, et al.
Publicado: (2012)

A Perturbed Ubiquitin Landscape Distinguishes Between Ubiquitin in Trafficking and in Proteolysis
por: Ziv, Inbal, et al.
Publicado: (2011)

Base-CP proteasome can serve as a platform for stepwise lid formation
por: Yu, Zanlin, et al.
Publicado: (2015)

Characteristics and Outcomes of Young Patients with First-Ever Ischemic Stroke Compared to Older Patients: The National Acute Stroke ISraeli Registry
por: Lutski, Miri, et al.
Publicado: (2017)

New onset diabetes in adulthood is associated with a substantial risk for mortality at all ages: a population based historical cohort study with a decade-long follow-up
por: Zucker, Inbar, et al.
Publicado: (2017)

miRNAminer: A tool for homologous microRNA gene search
por: Artzi, Shay, et al.
Publicado: (2008)

A High Affinity hRpn2-Derived Peptide That Displaces Human Rpn13 from Proteasome in 293T Cells
por: Lu, Xiuxiu, et al.
Publicado: (2015)

Subtle Alterations in PCNA-Partner Interactions Severely Impair DNA Replication and Repair
por: Fridman, Yearit, et al.
Publicado: (2010)

Reverse PCA, a Systematic Approach for Identifying Genes Important for the Physical Interaction between Protein Pairs
por: Lev, Ifat, et al.
Publicado: (2013)

Cerebral Autoregulation Real-Time Monitoring
por: Tsalach, Adi, et al.
Publicado: (2016)

Regional gaps in the provision of inpatient rehabilitation services for the elderly in Israel: Results of a national survey
por: Zucker, Inbar, et al.
Publicado: (2013)

Mechanism of the Rpn13-induced activation of Uch37
por: Jiao, Lianying, et al.
Publicado: (2014)

Generalized joint hypermobility, scoliosis, patellofemoral pain, and physical abilities in young dancers
por: Steinberg, Nili, et al.
Publicado: (2021)

Nuclear import of an intact preassembled proteasome particle
por: Savulescu, Anca F., et al.
Publicado: (2011)

Altered ubiquitin signaling induces Alzheimer’s disease-like hallmarks in a three-dimensional human neural cell culture model
por: Maniv, Inbal, et al.
Publicado: (2023)

The Elg1 Clamp Loader Plays a Role in Sister Chromatid Cohesion
por: Parnas, Oren, et al.
Publicado: (2009)

Biogenesis of RNA Polymerases II and III Requires the Conserved GPN Small GTPases in Saccharomyces cerevisiae
por: Minaker, Sean W., et al.
Publicado: (2013)

Chemical inhibitors of Candida albicans hyphal morphogenesis target endocytosis
por: Bar-Yosef, Hagit, et al.
Publicado: (2017)

Invited Perspective: Air Pollution and Congenital Heart Defects (CHDs)—a Summary of Two Decades and Future Direction in Research
por: Agay-Shay, Keren
Publicado: (2023)

Mitotic Spindle Disruption by Alternating Electric Fields Leads to Improper Chromosome Segregation and Mitotic Catastrophe in Cancer Cells
por: Giladi, Moshe, et al.
Publicado: (2015)

Covalent Rpn13-Binding Inhibitors for the Treatment of Ovarian Cancer
por: Anchoori, Ravi K., et al.
Publicado: (2018)

Proteasome Nuclear Activity Affects Chromosome Stability by Controlling the Turnover of Mms22, a Protein Important for DNA Repair
por: Ben-Aroya, Shay, et al.
Publicado: (2010)

New early phenotypic markers for cucumber green mottle mosaic virus disease in cucumbers exposed to fluctuating extreme temperatures
por: Molad, Ori, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_kun9rjmek191lmsn92iid4tgav