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A regulatory circuit of miR-125b/miR-20b and Wnt signalling controls glioblastoma phenotypes through FZD6-modulated pathways

Molecularly defined subclassification is associated with phenotypic malignancy of glioblastoma (GBM). However, current understanding of the molecular basis of subclass conversion that is often involved in GBM recurrence remain rudimentary at best. Here we report that canonical Wnt signalling that is...

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Detalles Bibliográficos
Autores principales:	Huang, Tianzhi, Alvarez, Angel A., Pangeni, Rajendra P., M. Horbinski, Craig, Lu, Songjian, Kim, Sung-Hak, James, C. David, J. Raizer, Jeffery, A. Kessler, John, Brenann, Cameron W., Sulman, Erik P., Finocchiaro, Gaetano, Tan, Ming, Nishikawa, Ryo, Lu, Xinghua, Nakano, Ichiro, Hu, Bo, Cheng, Shi-Yuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059456/ https://www.ncbi.nlm.nih.gov/pubmed/27698350 http://dx.doi.org/10.1038/ncomms12885

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