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Divergent effects of central melanocortin signalling on fat and sucrose preference in humans

Melanocortin-4-receptor (MC4R)-expressing neurons modulate food intake and preference in rodents but their role in human food preference is unknown. Here we show that compared with lean and weight-matched controls, MC4R deficient individuals exhibited a markedly increased preference for high fat, bu...

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Detalles Bibliográficos
Autores principales:	van der Klaauw, Agatha A., Keogh, Julia M., Henning, Elana, Stephenson, Cheryl, Kelway, Sarah, Trowse, Victoria M., Subramanian, Naresh, O'Rahilly, Stephen, Fletcher, Paul C., Farooqi, I. Sadaf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059464/ https://www.ncbi.nlm.nih.gov/pubmed/27701398 http://dx.doi.org/10.1038/ncomms13055

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