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Bmi1 marks distinct castration-resistant luminal progenitor cells competent for prostate regeneration and tumour initiation

Identification of defined cell populations with stem/progenitor properties is key for understanding prostate development and tumorigenesis. Here we show that the polycomb repressor protein Bmi1 marks a population of castration-resistant luminal epithelial cells enriched in the mouse proximal prostat...

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Detalles Bibliográficos
Autores principales:	Yoo, Young A., Roh, Meejeon, Naseem, Anum F., Lysy, Barbara, Desouki, Mohamed M., Unno, Kenji, Abdulkadir, Sarki A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059479/ https://www.ncbi.nlm.nih.gov/pubmed/27703144 http://dx.doi.org/10.1038/ncomms12943

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