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Chinese Herbal Medicine for Postpartum Depression: A Systematic Review of Randomized Controlled Trials
Background. Postpartum depression (PPD) does great harm to women following childbirth. The aim of this study was to conduct a systematic review of the literature to assess the efficacy and safety of CHM for the treatment of PPD. Methods. Published or ongoing registered trials were searched for from...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059536/ https://www.ncbi.nlm.nih.gov/pubmed/27774110 http://dx.doi.org/10.1155/2016/5284234 |
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author | Li, Yongle Chen, Zijie Yu, Ning Yao, Keyu Che, Yiwen Xi, Yupeng Zhai, Shuangqing |
author_facet | Li, Yongle Chen, Zijie Yu, Ning Yao, Keyu Che, Yiwen Xi, Yupeng Zhai, Shuangqing |
author_sort | Li, Yongle |
collection | PubMed |
description | Background. Postpartum depression (PPD) does great harm to women following childbirth. The aim of this study was to conduct a systematic review of the literature to assess the efficacy and safety of CHM for the treatment of PPD. Methods. Published or ongoing registered trials were searched for from the inception of the various databases to December 31, 2015. Data extraction and methodology assessment were conducted independently by two researchers. RevMan 5.3 software was used to analyze the data. Results. Forty-seven registered clinical trials (RCTs) were identified and reviewed. The results showed CHM alone or in combination with routine treatments could reduce HAMD score, EPDS score, incidence of adverse events, TESS, and SERS. CHM combined with routine treatment was more effective in increasing serum estradiol levels and reducing progesterone levels than routine treatment alone. Meanwhile, pooled data revealed that MRLQS combined with routine treatments or MRLQS plus MSHS combined with routine treatments were more effective than other therapeutic methods in TCM. MRLQS plus MSHS alone was found to be an effective alternative when compared to routine treatments. Conclusions. This review suggested that CHM was safe and effective in the treatment of PPD. However, this could not be proven conclusively. To ensure evidence-based clinical practice, more rigorously designed trials are warranted. |
format | Online Article Text |
id | pubmed-5059536 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-50595362016-10-23 Chinese Herbal Medicine for Postpartum Depression: A Systematic Review of Randomized Controlled Trials Li, Yongle Chen, Zijie Yu, Ning Yao, Keyu Che, Yiwen Xi, Yupeng Zhai, Shuangqing Evid Based Complement Alternat Med Review Article Background. Postpartum depression (PPD) does great harm to women following childbirth. The aim of this study was to conduct a systematic review of the literature to assess the efficacy and safety of CHM for the treatment of PPD. Methods. Published or ongoing registered trials were searched for from the inception of the various databases to December 31, 2015. Data extraction and methodology assessment were conducted independently by two researchers. RevMan 5.3 software was used to analyze the data. Results. Forty-seven registered clinical trials (RCTs) were identified and reviewed. The results showed CHM alone or in combination with routine treatments could reduce HAMD score, EPDS score, incidence of adverse events, TESS, and SERS. CHM combined with routine treatment was more effective in increasing serum estradiol levels and reducing progesterone levels than routine treatment alone. Meanwhile, pooled data revealed that MRLQS combined with routine treatments or MRLQS plus MSHS combined with routine treatments were more effective than other therapeutic methods in TCM. MRLQS plus MSHS alone was found to be an effective alternative when compared to routine treatments. Conclusions. This review suggested that CHM was safe and effective in the treatment of PPD. However, this could not be proven conclusively. To ensure evidence-based clinical practice, more rigorously designed trials are warranted. Hindawi Publishing Corporation 2016 2016-09-28 /pmc/articles/PMC5059536/ /pubmed/27774110 http://dx.doi.org/10.1155/2016/5284234 Text en Copyright © 2016 Yongle Li et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Li, Yongle Chen, Zijie Yu, Ning Yao, Keyu Che, Yiwen Xi, Yupeng Zhai, Shuangqing Chinese Herbal Medicine for Postpartum Depression: A Systematic Review of Randomized Controlled Trials |
title | Chinese Herbal Medicine for Postpartum Depression: A Systematic Review of Randomized Controlled Trials |
title_full | Chinese Herbal Medicine for Postpartum Depression: A Systematic Review of Randomized Controlled Trials |
title_fullStr | Chinese Herbal Medicine for Postpartum Depression: A Systematic Review of Randomized Controlled Trials |
title_full_unstemmed | Chinese Herbal Medicine for Postpartum Depression: A Systematic Review of Randomized Controlled Trials |
title_short | Chinese Herbal Medicine for Postpartum Depression: A Systematic Review of Randomized Controlled Trials |
title_sort | chinese herbal medicine for postpartum depression: a systematic review of randomized controlled trials |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059536/ https://www.ncbi.nlm.nih.gov/pubmed/27774110 http://dx.doi.org/10.1155/2016/5284234 |
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