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Control of ADAM17 activity by regulation of its cellular localisation

An important, irreversible step in many signalling pathways is the shedding of membrane-anchored proteins. A Disintegrin And Metalloproteinase (ADAM) 17 is one of the major sheddases involved in a variety of physiological and pathophysiological processes including regeneration, differentiation, and...

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Detalles Bibliográficos
Autores principales: Lorenzen, Inken, Lokau, Juliane, Korpys, Yvonne, Oldefest, Mirja, Flynn, Charlotte M., Künzel, Ulrike, Garbers, Christoph, Freeman, Matthew, Grötzinger, Joachim, Düsterhöft, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059621/
https://www.ncbi.nlm.nih.gov/pubmed/27731361
http://dx.doi.org/10.1038/srep35067