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A Rough Energy Landscape to Describe Surface-Linked Antibody and Antigen Bond Formation
Antibodies and B cell receptors often bind their antigen at cell-cell interface while both molecular species are surface-bound, which impacts bond kinetics and function. Despite the description of complex energy landscapes for dissociation kinetics which may also result in significantly different as...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059681/ https://www.ncbi.nlm.nih.gov/pubmed/27731375 http://dx.doi.org/10.1038/srep35193 |