A humanized mouse model for sequestration of Plasmodium falciparum sexual stages and in vivo evaluation of gametocytidal drugs

The development of new drugs to disrupt malaria transmission requires the establishment of an in vivo model to address the biology of Plasmodium falciparum sexual stages (gametocytes). Herein we show that chemically immune-modulated NSG mice grafted with human erythrocytes support complete sexual de...

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Detalles Bibliográficos
Autores principales: Duffier, Yoann, Lorthiois, Audrey, Cisteró, Pau, Dupuy, Florian, Jouvion, Grégory, Fiette, Laurence, Mazier, Dominique, Mayor, Alfredo, Lavazec, Catherine, Moreno Sabater, Alicia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059736/
https://www.ncbi.nlm.nih.gov/pubmed/27731362
http://dx.doi.org/10.1038/srep35025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059736/
https://www.ncbi.nlm.nih.gov/pubmed/27731362
http://dx.doi.org/10.1038/srep35025

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