mTOR is critical for intestinal T-cell homeostasis and resistance to Citrobacter rodentium

T-cells play an important role in promoting mucosal immunity against pathogens, but the mechanistic basis for their homeostasis in the intestine is still poorly understood. We report here that T-cell-specific deletion of mTOR results in dramatically decreased CD4 and CD8 T-cell numbers in the lamina...

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Detalles Bibliográficos
Autores principales: Lin, Xingguang, Yang, Jialong, Wang, Jinli, Huang, Hongxiang, Wang, Hong-Xia, Chen, Pengcheng, Wang, Shang, Pan, Yun, Qiu, Yu-Rong, Taylor, Gregory A., Vallance, Bruce A., Gao, Jimin, Zhong, Xiao-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059740/
https://www.ncbi.nlm.nih.gov/pubmed/27731345
http://dx.doi.org/10.1038/srep34939

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