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An essential developmental function for murine phosphoglycolate phosphatase in safeguarding cell proliferation

Mammalian phosphoglycolate phosphatase (PGP) is thought to target phosphoglycolate, a 2-deoxyribose fragment derived from the repair of oxidative DNA lesions. However, the physiological role of this activity and the biological function of the DNA damage product phosphoglycolate is unknown. We now sh...

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Detalles Bibliográficos
Autores principales: Segerer, Gabriela, Hadamek, Kerstin, Zundler, Matthias, Fekete, Agnes, Seifried, Annegrit, Mueller, Martin J., Koentgen, Frank, Gessler, Manfred, Jeanclos, Elisabeth, Gohla, Antje
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059750/
https://www.ncbi.nlm.nih.gov/pubmed/27731369
http://dx.doi.org/10.1038/srep35160