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An essential developmental function for murine phosphoglycolate phosphatase in safeguarding cell proliferation
Mammalian phosphoglycolate phosphatase (PGP) is thought to target phosphoglycolate, a 2-deoxyribose fragment derived from the repair of oxidative DNA lesions. However, the physiological role of this activity and the biological function of the DNA damage product phosphoglycolate is unknown. We now sh...
Autores principales: | Segerer, Gabriela, Hadamek, Kerstin, Zundler, Matthias, Fekete, Agnes, Seifried, Annegrit, Mueller, Martin J., Koentgen, Frank, Gessler, Manfred, Jeanclos, Elisabeth, Gohla, Antje |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059750/ https://www.ncbi.nlm.nih.gov/pubmed/27731369 http://dx.doi.org/10.1038/srep35160 |
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