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An interdigit signalling centre instructs coordinate phalanx-joint formation governed by 5′Hoxd–Gli3 antagonism

The number of phalanges and joints are key features of digit ‘identity' and are central to limb functionality and evolutionary adaptation. Prior chick work indicated that digit phalanges and their associated joints arise in a different manner than the more sparsely jointed long bones, and their...

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Detalles Bibliográficos
Autores principales: Huang, Bau-Lin, Trofka, Anna, Furusawa, Aki, Norrie, Jacqueline L., Rabinowitz, Adam H., Vokes, Steven A., Mark Taketo, M., Zakany, Jozsef, Mackem, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059757/
https://www.ncbi.nlm.nih.gov/pubmed/27713395
http://dx.doi.org/10.1038/ncomms12903

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