Abundant DNA 6mA methylation during early embryogenesis of zebrafish and pig

DNA N(6)-methyldeoxyadenosine (6mA) is a well-known prokaryotic DNA modification that has been shown to exist and play epigenetic roles in eukaryotic DNA. Here we report that 6mA accumulates up to ∼0.1–0.2% of total deoxyadenosine during early embryogenesis of vertebrates, but diminishes to the back...

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Detalles Bibliográficos
Autores principales: Liu, Jianzhao, Zhu, Yuanxiang, Luo, Guan-Zheng, Wang, Xinxia, Yue, Yanan, Wang, Xiaona, Zong, Xin, Chen, Kai, Yin, Hang, Fu, Ye, Han, Dali, Wang, Yizhen, Chen, Dahua, He, Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059759/
https://www.ncbi.nlm.nih.gov/pubmed/27713410
http://dx.doi.org/10.1038/ncomms13052

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