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Methods of synthesis of hydrogels … A review
Hydrogels are being investigated recently for the bioactive molecules (in particular pharmaceutical proteins) controlled release, such as matrices, and for the living cells encapsulation. Biodegradable nature of hydrogels has created much interest for drug delivery systems. The original three-dimens...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059832/ https://www.ncbi.nlm.nih.gov/pubmed/27752227 http://dx.doi.org/10.1016/j.jsps.2015.03.022 |
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author | Akhtar, Muhammad Faheem Hanif, Muhammad Ranjha, Nazar Muhammad |
author_facet | Akhtar, Muhammad Faheem Hanif, Muhammad Ranjha, Nazar Muhammad |
author_sort | Akhtar, Muhammad Faheem |
collection | PubMed |
description | Hydrogels are being investigated recently for the bioactive molecules (in particular pharmaceutical proteins) controlled release, such as matrices, and for the living cells encapsulation. Biodegradable nature of hydrogels has created much interest for drug delivery systems. The original three-dimensional structure disintegrates into nontoxic substances to ascertain an excellent biocompatibility of the gel. Chemical cross-linking is the highly resourceful method for the formation of hydrogels having an excellent mechanical strength. Cross-linkers used in hydrogel preparation should be extracted from the hydrogels before use due to their reported toxicity. Physically cross-linked methods for preparation of hydrogel are the alternate solution of cross-linker toxicity. |
format | Online Article Text |
id | pubmed-5059832 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-50598322016-10-17 Methods of synthesis of hydrogels … A review Akhtar, Muhammad Faheem Hanif, Muhammad Ranjha, Nazar Muhammad Saudi Pharm J Review Hydrogels are being investigated recently for the bioactive molecules (in particular pharmaceutical proteins) controlled release, such as matrices, and for the living cells encapsulation. Biodegradable nature of hydrogels has created much interest for drug delivery systems. The original three-dimensional structure disintegrates into nontoxic substances to ascertain an excellent biocompatibility of the gel. Chemical cross-linking is the highly resourceful method for the formation of hydrogels having an excellent mechanical strength. Cross-linkers used in hydrogel preparation should be extracted from the hydrogels before use due to their reported toxicity. Physically cross-linked methods for preparation of hydrogel are the alternate solution of cross-linker toxicity. Elsevier 2016-09 2015-03-21 /pmc/articles/PMC5059832/ /pubmed/27752227 http://dx.doi.org/10.1016/j.jsps.2015.03.022 Text en © 2015 The Authors. Production and hosting by Elsevier B.V. on behalf of King Saud University. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Review Akhtar, Muhammad Faheem Hanif, Muhammad Ranjha, Nazar Muhammad Methods of synthesis of hydrogels … A review |
title | Methods of synthesis of hydrogels … A review |
title_full | Methods of synthesis of hydrogels … A review |
title_fullStr | Methods of synthesis of hydrogels … A review |
title_full_unstemmed | Methods of synthesis of hydrogels … A review |
title_short | Methods of synthesis of hydrogels … A review |
title_sort | methods of synthesis of hydrogels … a review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059832/ https://www.ncbi.nlm.nih.gov/pubmed/27752227 http://dx.doi.org/10.1016/j.jsps.2015.03.022 |
work_keys_str_mv | AT akhtarmuhammadfaheem methodsofsynthesisofhydrogelsareview AT hanifmuhammad methodsofsynthesisofhydrogelsareview AT ranjhanazarmuhammad methodsofsynthesisofhydrogelsareview |