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Methods of synthesis of hydrogels … A review

Hydrogels are being investigated recently for the bioactive molecules (in particular pharmaceutical proteins) controlled release, such as matrices, and for the living cells encapsulation. Biodegradable nature of hydrogels has created much interest for drug delivery systems. The original three-dimens...

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Detalles Bibliográficos
Autores principales: Akhtar, Muhammad Faheem, Hanif, Muhammad, Ranjha, Nazar Muhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059832/
https://www.ncbi.nlm.nih.gov/pubmed/27752227
http://dx.doi.org/10.1016/j.jsps.2015.03.022
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author Akhtar, Muhammad Faheem
Hanif, Muhammad
Ranjha, Nazar Muhammad
author_facet Akhtar, Muhammad Faheem
Hanif, Muhammad
Ranjha, Nazar Muhammad
author_sort Akhtar, Muhammad Faheem
collection PubMed
description Hydrogels are being investigated recently for the bioactive molecules (in particular pharmaceutical proteins) controlled release, such as matrices, and for the living cells encapsulation. Biodegradable nature of hydrogels has created much interest for drug delivery systems. The original three-dimensional structure disintegrates into nontoxic substances to ascertain an excellent biocompatibility of the gel. Chemical cross-linking is the highly resourceful method for the formation of hydrogels having an excellent mechanical strength. Cross-linkers used in hydrogel preparation should be extracted from the hydrogels before use due to their reported toxicity. Physically cross-linked methods for preparation of hydrogel are the alternate solution of cross-linker toxicity.
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spelling pubmed-50598322016-10-17 Methods of synthesis of hydrogels … A review Akhtar, Muhammad Faheem Hanif, Muhammad Ranjha, Nazar Muhammad Saudi Pharm J Review Hydrogels are being investigated recently for the bioactive molecules (in particular pharmaceutical proteins) controlled release, such as matrices, and for the living cells encapsulation. Biodegradable nature of hydrogels has created much interest for drug delivery systems. The original three-dimensional structure disintegrates into nontoxic substances to ascertain an excellent biocompatibility of the gel. Chemical cross-linking is the highly resourceful method for the formation of hydrogels having an excellent mechanical strength. Cross-linkers used in hydrogel preparation should be extracted from the hydrogels before use due to their reported toxicity. Physically cross-linked methods for preparation of hydrogel are the alternate solution of cross-linker toxicity. Elsevier 2016-09 2015-03-21 /pmc/articles/PMC5059832/ /pubmed/27752227 http://dx.doi.org/10.1016/j.jsps.2015.03.022 Text en © 2015 The Authors. Production and hosting by Elsevier B.V. on behalf of King Saud University. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review
Akhtar, Muhammad Faheem
Hanif, Muhammad
Ranjha, Nazar Muhammad
Methods of synthesis of hydrogels … A review
title Methods of synthesis of hydrogels … A review
title_full Methods of synthesis of hydrogels … A review
title_fullStr Methods of synthesis of hydrogels … A review
title_full_unstemmed Methods of synthesis of hydrogels … A review
title_short Methods of synthesis of hydrogels … A review
title_sort methods of synthesis of hydrogels … a review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059832/
https://www.ncbi.nlm.nih.gov/pubmed/27752227
http://dx.doi.org/10.1016/j.jsps.2015.03.022
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