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MiR-182-5p protects inner ear hair cells from cisplatin-induced apoptosis by inhibiting FOXO3a

Cisplatin is widely used for chemotherapy of a variety of malignancies. However, the clinical application of cisplatin is hampered by the resultant irreversible hearing loss due to hair cell apoptosis. To date, no practical regimen to resolve this has been developed. Meanwhile, the role of microRNA...

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Detalles Bibliográficos
Autores principales: Li, Yimeng, Li, Ao, Wu, Jingfang, He, Yingzi, Yu, Huiqian, Chai, Renjie, Li, Huawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059852/
https://www.ncbi.nlm.nih.gov/pubmed/27607577
http://dx.doi.org/10.1038/cddis.2016.246

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