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MiR-182-5p protects inner ear hair cells from cisplatin-induced apoptosis by inhibiting FOXO3a
Cisplatin is widely used for chemotherapy of a variety of malignancies. However, the clinical application of cisplatin is hampered by the resultant irreversible hearing loss due to hair cell apoptosis. To date, no practical regimen to resolve this has been developed. Meanwhile, the role of microRNA...
Autores principales: | Li, Yimeng, Li, Ao, Wu, Jingfang, He, Yingzi, Yu, Huiqian, Chai, Renjie, Li, Huawei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059852/ https://www.ncbi.nlm.nih.gov/pubmed/27607577 http://dx.doi.org/10.1038/cddis.2016.246 |
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