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Kinsenoside screening with a microfluidic chip attenuates gouty arthritis through inactivating NF-κB signaling in macrophages and protecting endothelial cells
Gouty arthritis is a rheumatic disease that is characterized by the deposition of monosodium urate (MSU) in synovial joints cause by the increased serum hyperuricemia. This study used a three-dimensional (3D) flowing microfluidic chip to screen the effective candidate against MSU-stimulated human um...
Autores principales: | Han, Qiao, Bing, Wang, Di, Yin, Hua, Li, Shi-he, Li, Yu-hua, Zheng, Xiu-guo, Han, Yu-gang, Wang, Qi-ming, Fan, Shih-mo, Yang, Ting-ting, Tang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059859/ https://www.ncbi.nlm.nih.gov/pubmed/27584788 http://dx.doi.org/10.1038/cddis.2016.255 |
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