Overexpression of JARID1B promotes differentiation via SHIP1/AKT signaling in human hypopharyngeal squamous cell carcinoma

Histone H3 (H3K4) demethylase JARID1B is aberrantly upregulated in many types of tumor and has been proposed to function as oncogene. Here we show that JARID1B is elevated in moderate and high-differentiated human hypopharyngeal squamous cell carcinoma (HPSCC) compared with low-differentiated HPSCC....

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Detalles Bibliográficos
Autores principales: Zhang, Jisheng, An, Xiaofei, Han, Yafei, Ma, Rui, Yang, Kun, Zhang, Lu, Chi, Jingwei, Li, Wei, Llobet-Navas, David, Xu, Yan, Jiang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059865/
https://www.ncbi.nlm.nih.gov/pubmed/27584795
http://dx.doi.org/10.1038/cddis.2016.262

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