Long noncoding RNAs in the progression, metastasis, and prognosis of osteosarcoma

Long noncoding RNAs (lncRNAs) are a class of non-protein-coding molecules longer than 200 nucleotides that are involved in the development and progression of many types of tumors. Numerous lncRNAs regulate cell proliferation, metastasis, and chemotherapeutic drug resistance. Osteosarcoma is one of t...

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Autores principales: Yang, Zuozhang, Li, Xiaojuan, Yang, Yihao, He, Zewei, Qu, Xin, Zhang, Ya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059871/
https://www.ncbi.nlm.nih.gov/pubmed/27685633
http://dx.doi.org/10.1038/cddis.2016.272
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author Yang, Zuozhang
Li, Xiaojuan
Yang, Yihao
He, Zewei
Qu, Xin
Zhang, Ya
author_facet Yang, Zuozhang
Li, Xiaojuan
Yang, Yihao
He, Zewei
Qu, Xin
Zhang, Ya
author_sort Yang, Zuozhang
collection PubMed
description Long noncoding RNAs (lncRNAs) are a class of non-protein-coding molecules longer than 200 nucleotides that are involved in the development and progression of many types of tumors. Numerous lncRNAs regulate cell proliferation, metastasis, and chemotherapeutic drug resistance. Osteosarcoma is one of the main bone tumor subtypes that poses a serious threat to adolescent health. We summarized how lncRNAs regulate osteosarcoma progression, invasion, and drug resistance, as well as how lncRNAs can function as biomarkers or independent prognostic indicators with respect to osteosarcoma therapy.
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spelling pubmed-50598712016-10-26 Long noncoding RNAs in the progression, metastasis, and prognosis of osteosarcoma Yang, Zuozhang Li, Xiaojuan Yang, Yihao He, Zewei Qu, Xin Zhang, Ya Cell Death Dis Review Long noncoding RNAs (lncRNAs) are a class of non-protein-coding molecules longer than 200 nucleotides that are involved in the development and progression of many types of tumors. Numerous lncRNAs regulate cell proliferation, metastasis, and chemotherapeutic drug resistance. Osteosarcoma is one of the main bone tumor subtypes that poses a serious threat to adolescent health. We summarized how lncRNAs regulate osteosarcoma progression, invasion, and drug resistance, as well as how lncRNAs can function as biomarkers or independent prognostic indicators with respect to osteosarcoma therapy. Nature Publishing Group 2016-09 2016-09-29 /pmc/articles/PMC5059871/ /pubmed/27685633 http://dx.doi.org/10.1038/cddis.2016.272 Text en Copyright © 2016 The Author(s) http://creativecommons.org/licenses/by/4.0/ Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Review
Yang, Zuozhang
Li, Xiaojuan
Yang, Yihao
He, Zewei
Qu, Xin
Zhang, Ya
Long noncoding RNAs in the progression, metastasis, and prognosis of osteosarcoma
title Long noncoding RNAs in the progression, metastasis, and prognosis of osteosarcoma
title_full Long noncoding RNAs in the progression, metastasis, and prognosis of osteosarcoma
title_fullStr Long noncoding RNAs in the progression, metastasis, and prognosis of osteosarcoma
title_full_unstemmed Long noncoding RNAs in the progression, metastasis, and prognosis of osteosarcoma
title_short Long noncoding RNAs in the progression, metastasis, and prognosis of osteosarcoma
title_sort long noncoding rnas in the progression, metastasis, and prognosis of osteosarcoma
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059871/
https://www.ncbi.nlm.nih.gov/pubmed/27685633
http://dx.doi.org/10.1038/cddis.2016.272
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