4-cholesten-3-one suppresses lung adenocarcinoma metastasis by regulating translocation of HMGB1, HIF1α and Caveolin-1

Metastasis is a great challenge in lung adenocarcinoma (ADC) therapy. Cholesterol has been implicated in ADC metastasis. 4-cholesten-3-one, as cholesterol metabolite and analog, can substitute membrane cholesterol and increase membrane fluidity. In this study, we explored the possibility that 4-chol...

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Detalles Bibliográficos
Autores principales: Ma, Jinben, Fu, Guobin, Wu, Jing, Han, Shaoxian, Zhang, Lishan, Yang, Ming, Yu, Yong, Zhang, Mengyuan, Lin, Yanliang, Wang, Yibing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059879/
https://www.ncbi.nlm.nih.gov/pubmed/27899819
http://dx.doi.org/10.1038/cddis.2016.281

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