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Capsaicin mediates caspases activation and induces apoptosis through P38 and JNK MAPK pathways in human renal carcinoma
BACKGROUND: Renal cell carcinoma (RCC) is one of the tumors most refractory to chemotherapy to date. Therefore, novel therapeutic agents are urgently needed for this disease. Capsaicin (CPS), a natural active ingredient of green and red peppers, and a ligand of transient receptor potential vanilloid...
Autores principales: | Liu, Tao, Wang, Gang, Tao, Huangheng, Yang, Zhonghua, Wang, Yongzhi, Meng, Zhe, Cao, Rui, Xiao, Yu, Wang, Xinghuan, Zhou, Jiajie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059898/ https://www.ncbi.nlm.nih.gov/pubmed/27729033 http://dx.doi.org/10.1186/s12885-016-2831-y |
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