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Critical care provision after colorectal cancer surgery

BACKGROUND: Colorectal cancer (CRC) is the 2nd largest cause of cancer related mortality in the UK with 40 000 new patients being diagnosed each year. Complications of CRC surgery can occur in the perioperative period that leads to the requirement of organ support. The aim of this study was to ident...

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Autores principales: Dale, C. D., McLoone, P., Sloan, B., Kinsella, J., Morrison, D., Puxty, K., Quasim, T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059906/
https://www.ncbi.nlm.nih.gov/pubmed/27733119
http://dx.doi.org/10.1186/s12871-016-0243-9
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author Dale, C. D.
McLoone, P.
Sloan, B.
Kinsella, J.
Morrison, D.
Puxty, K.
Quasim, T.
author_facet Dale, C. D.
McLoone, P.
Sloan, B.
Kinsella, J.
Morrison, D.
Puxty, K.
Quasim, T.
author_sort Dale, C. D.
collection PubMed
description BACKGROUND: Colorectal cancer (CRC) is the 2nd largest cause of cancer related mortality in the UK with 40 000 new patients being diagnosed each year. Complications of CRC surgery can occur in the perioperative period that leads to the requirement of organ support. The aim of this study was to identify pre-operative risk factors that increased the likelihood of this occurring. METHODS: This is a retrospective observational study of all 6441 patients who underwent colorectal cancer surgery within the West of Scotland Region between 2005 and 2011. Logistic regression was employed to determine factors associated with receiving postoperative organ support. RESULTS: A total of 610 (9 %) patients received organ support. Multivariate analysis identified age ≥65, male gender, emergency surgery, social deprivation, heart failure and type II diabetes as being independently associated with organ support postoperatively. After adjusting for demographic and clinical factors, patients with metastatic disease appeared less likely to receive organ support (p = 0.012). CONCLUSIONS: Nearly one in ten patients undergoing CRC surgery receive organ support in the post operative period. We identified several risk factors which increase the likelihood of receiving organ support post operatively. This is relevant when consenting patients about the risks of CRC surgery.
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spelling pubmed-50599062016-10-24 Critical care provision after colorectal cancer surgery Dale, C. D. McLoone, P. Sloan, B. Kinsella, J. Morrison, D. Puxty, K. Quasim, T. BMC Anesthesiol Research Article BACKGROUND: Colorectal cancer (CRC) is the 2nd largest cause of cancer related mortality in the UK with 40 000 new patients being diagnosed each year. Complications of CRC surgery can occur in the perioperative period that leads to the requirement of organ support. The aim of this study was to identify pre-operative risk factors that increased the likelihood of this occurring. METHODS: This is a retrospective observational study of all 6441 patients who underwent colorectal cancer surgery within the West of Scotland Region between 2005 and 2011. Logistic regression was employed to determine factors associated with receiving postoperative organ support. RESULTS: A total of 610 (9 %) patients received organ support. Multivariate analysis identified age ≥65, male gender, emergency surgery, social deprivation, heart failure and type II diabetes as being independently associated with organ support postoperatively. After adjusting for demographic and clinical factors, patients with metastatic disease appeared less likely to receive organ support (p = 0.012). CONCLUSIONS: Nearly one in ten patients undergoing CRC surgery receive organ support in the post operative period. We identified several risk factors which increase the likelihood of receiving organ support post operatively. This is relevant when consenting patients about the risks of CRC surgery. BioMed Central 2016-10-12 /pmc/articles/PMC5059906/ /pubmed/27733119 http://dx.doi.org/10.1186/s12871-016-0243-9 Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Dale, C. D.
McLoone, P.
Sloan, B.
Kinsella, J.
Morrison, D.
Puxty, K.
Quasim, T.
Critical care provision after colorectal cancer surgery
title Critical care provision after colorectal cancer surgery
title_full Critical care provision after colorectal cancer surgery
title_fullStr Critical care provision after colorectal cancer surgery
title_full_unstemmed Critical care provision after colorectal cancer surgery
title_short Critical care provision after colorectal cancer surgery
title_sort critical care provision after colorectal cancer surgery
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059906/
https://www.ncbi.nlm.nih.gov/pubmed/27733119
http://dx.doi.org/10.1186/s12871-016-0243-9
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