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Sequential high-content profiling of the IgG-autoantibody repertoire reveals novel antigens in rheumatoid arthritis

BACKGROUND: The aim was to identify novel diagnostic autoantibody candidates for rheumatoid arthritis (RA) by comprehensive screening for autoreactivity. METHOD: We incubated 5892 recombinant proteins coupled to fluorescent beads, with patients’ sera for the detection of IgG-autoantibodies in three...

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Detalles Bibliográficos
Autores principales:	Vordenbäumen, Stefan, Lueking, Angelika, Budde, Petra, Zucht, Hans-Dieter, Goehler, Heike, Brinks, Ralph, Fischer-Betz, Rebecca, Richter, Jutta, Bleck, Ellen, Detert, Jacqueline, Langer, Hans-Eckhard, Sörgel, Anne, Burmester, Gerd-Rüdiger, Schulz-Knappe, Peter, Schneider, Matthias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059912/ https://www.ncbi.nlm.nih.gov/pubmed/27729089 http://dx.doi.org/10.1186/s13075-016-1135-6

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