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The Toxoplasma gondii rhoptry protein ROP18 is an Irga6‐specific kinase and regulated by the dense granule protein GRA7

In mice, avirulent strains (e.g. types II and III) of the protozoan parasite Toxoplasma gondii are restricted by the immunity‐related GTPase (IRG) resistance system. Loading of IRG proteins onto the parasitophorous vacuolar membrane (PVM) is required for vacuolar rupture resulting in parasite cleara...

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Detalles Bibliográficos
Autores principales: Hermanns, Thomas, Müller, Urs B., Könen‐Waisman, Stephanie, Howard, Jonathan C., Steinfeldt, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061101/
https://www.ncbi.nlm.nih.gov/pubmed/26247512
http://dx.doi.org/10.1111/cmi.12499