Cargando…

The Toxoplasma gondii rhoptry protein ROP18 is an Irga6‐specific kinase and regulated by the dense granule protein GRA7

In mice, avirulent strains (e.g. types II and III) of the protozoan parasite Toxoplasma gondii are restricted by the immunity‐related GTPase (IRG) resistance system. Loading of IRG proteins onto the parasitophorous vacuolar membrane (PVM) is required for vacuolar rupture resulting in parasite cleara...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hermanns, Thomas, Müller, Urs B., Könen‐Waisman, Stephanie, Howard, Jonathan C., Steinfeldt, Tobias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2015
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061101/ https://www.ncbi.nlm.nih.gov/pubmed/26247512 http://dx.doi.org/10.1111/cmi.12499

Ejemplares similares

Screening of apical membrane antigen-1 (AMA1), dense granule protein-7 (GRA7) and rhoptry protein-16 (ROP16) antigens for a potential vaccine candidate against Toxoplasma gondii for chickens
por: Madlala, Thabile, et al.
Publicado: (2023)

Screening and Identification of the Host Proteins Interacting with Toxoplasma gondii Rhoptry Protein ROP16
por: Pan, Ming, et al.
Publicado: (2017)

The Rhoptry Proteins ROP18 and ROP5 Mediate Toxoplasma gondii Evasion of the Murine, But Not the Human, Interferon-Gamma Response
por: Niedelman, Wendy, et al.
Publicado: (2012)

ROP18 Is a Rhoptry Kinase Controlling the Intracellular Proliferation of Toxoplasma gondii
por: El Hajj, Hiba, et al.
Publicado: (2007)

Dense Granule Protein GRA64 Interacts with Host Cell ESCRT Proteins during Toxoplasma gondii Infection
por: Mayoral, Joshua, et al.
Publicado: (2022)

Rhoptry Proteins ROP5 and ROP18 Are Major Murine Virulence Factors in Genetically Divergent South American Strains of Toxoplasma gondii
por: Behnke, Michael S., et al.
Publicado: (2015)

Selective and strain-specific NFAT4 activation by the Toxoplasma gondii polymorphic dense granule protein GRA6
por: Ma, Ji Su, et al.
Publicado: (2014)

The Toxoplasma gondii dense granule protein TgGRA3 interacts with host Golgi and dysregulates anterograde transport
por: Deffieu, Maika S., et al.
Publicado: (2019)

Secretion of Rhoptry and Dense Granule Effector Proteins by Nonreplicating Toxoplasma gondii Uracil Auxotrophs Controls the Development of Antitumor Immunity
por: Fox, Barbara A., et al.
Publicado: (2016)

A Toxoplasma gondii Pseudokinase Inhibits Host IRG Resistance Proteins
por: Fleckenstein, Martin C., et al.
Publicado: (2012)

Immune Protection of Rhoptry Protein 21 (ROP21) of Toxoplasma gondii as a DNA Vaccine Against Toxoplasmosis
por: Zhang, Zhenchao, et al.
Publicado: (2018)

Translocation of Dense Granule Effectors across the Parasitophorous Vacuole Membrane in Toxoplasma-Infected Cells Requires the Activity of ROP17, a Rhoptry Protein Kinase
por: Panas, Michael W., et al.
Publicado: (2019)

The Rhoptry Pseudokinase ROP54 Modulates Toxoplasma gondii Virulence and Host GBP2 Loading
por: Kim, Elliot W., et al.
Publicado: (2016)

Strain-specific activation of the NF-κB pathway by GRA15, a novel Toxoplasma gondii dense granule protein
por: Rosowski, Emily E., et al.
Publicado: (2011)

Differential Impacts on Host Transcription by ROP and GRA Effectors from the Intracellular Parasite Toxoplasma gondii
por: Rastogi, Suchita, et al.
Publicado: (2020)

Phenotypes Associated with Knockouts of Eight Dense Granule Gene Loci (GRA2-9) in Virulent Toxoplasma gondii
por: Rommereim, Leah M., et al.
Publicado: (2016)

Rhoptry kinase protein 39 (ROP39) is a novel factor that recruits host mitochondria to the parasitophorous vacuole of Toxoplasma gondii
por: Fukumoto, Junpei, et al.
Publicado: (2021)

Rhoptry and Dense Granule Secreted Effectors Regulate CD8(+) T Cell Recognition of Toxoplasma gondii Infected Host Cells
por: Rommereim, Leah M., et al.
Publicado: (2019)

Neighbors Working Together: a Toxoplasma Rhoptry Protein That Facilitates Dense Granule Protein Translocation into the Host Cell
por: Arrizabalaga, Gustavo
Publicado: (2019)

Ferlins and TgDOC2 in Toxoplasma Microneme, Rhoptry and Dense Granule Secretion
por: Tagoe, Daniel N. A., et al.
Publicado: (2021)

Evaluation of recombinant granule antigens GRA1 and GRA7 for serodiagnosis of Toxoplasma gondii infection in dogs
por: Wang, Zedong, et al.
Publicado: (2014)

The IFN-γ-Inducible GTPase, Irga6, Protects Mice against Toxoplasma gondii but Not against Plasmodium berghei and Some Other Intracellular Pathogens
por: Liesenfeld, Oliver, et al.
Publicado: (2011)

Construction and In vitro Expression Analyses of a DNA Plasmid Encoding Dense Granule GRA5 Antigen of Toxoplasma gondii
por: Babaie, Jalal, et al.
Publicado: (2011)

Activation of NF-κB signaling by the dense granule protein GRA15 of a newly isolated type 1 Toxoplasma gondii strain
por: Guo, Guanghao, et al.
Publicado: (2022)

The Toxoplasma gondii rhoptry protein ROP 2 is inserted into the parasitophorous vacuole membrane, surrounding the intracellular parasite, and is exposed to the host cell cytoplasm
Publicado: (1994)

Toxoplasma gondii Rhoptry Protein 7 (ROP7) Interacts with NLRP3 and Promotes Inflammasome Hyperactivation in THP-1-Derived Macrophages
por: Zhu, Lijun, et al.
Publicado: (2022)

Virus-Like Particles Expressing Toxoplasma gondii Rhoptry Protein 18 Induces Better Protection Than Rhoptry Protein 4 against T. gondii Infection
por: Kang, Hae-Ji, et al.
Publicado: (2018)

Phosphorylation of Mouse Immunity-Related GTPase (IRG) Resistance Proteins Is an Evasion Strategy for Virulent Toxoplasma gondii
por: Steinfeldt, Tobias, et al.
Publicado: (2010)

T. gondii rhoptry protein ROP18 induces apoptosis of neural cells via endoplasmic reticulum stress pathway
por: Wan, Lijuan, et al.
Publicado: (2015)

Toxoplasma gondii Parasitophorous Vacuole Membrane-Associated Dense Granule Proteins Orchestrate Chronic Infection and GRA12 Underpins Resistance to Host Gamma Interferon
por: Fox, Barbara A., et al.
Publicado: (2019)

Correction: Phosphorylation of Mouse Immunity-Related GTPase (IRG) Resistance Proteins Is an Evasion Strategy for Virulent Toxoplasma gondii
por: Steinfeldt, Tobias, et al.
Publicado: (2015)

Rhoptry antigens as Toxoplasma gondii vaccine target
por: Foroutan, Masoud, et al.
Publicado: (2019)

Protective efficacy of Toxoplasma gondii GRA12 or GRA7 recombinant proteins encapsulated in PLGA nanoparticles against acute Toxoplasma gondii infection in mice
por: Sun, Hong-chao, et al.
Publicado: (2023)

Protein targets of thiazolidinone derivatives in Toxoplasma gondii and insights into their binding to ROP18
por: Molina, Diego, et al.
Publicado: (2018)

First Characterization of the Neospora caninum Dense Granule Protein GRA9
por: Leineweber, Margret, et al.
Publicado: (2017)

The activation mechanism of Irga6, an interferon-inducible GTPase contributing to mouse resistance against Toxoplasma gondii
por: Pawlowski, Nikolaus, et al.
Publicado: (2011)

Cloning, expression and immunoreactivity of recombinant Toxoplasma gondii GRA5 protein
por: Arab-Mazar, Zahra, et al.
Publicado: (2016)

The Toxoplasma gondii Rhoptry Kinome Is Essential for Chronic Infection
por: Fox, Barbara A., et al.
Publicado: (2016)

Toxoplasma gondii virulence prediction using hierarchical cluster analysis based on coding sequences (CDS) of sag1, gra7 and rop18
por: Subekti, Didik T, et al.
Publicado: (2021)

Proximity biotinylation reveals novel secreted dense granule proteins of Toxoplasma gondii bradyzoites
por: Nadipuram, Santhosh Mukund, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_lotvjn9dp5g45gqo5ghvf58j8s