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Replicative Senescence in Human Fibroblasts Is Delayed by Hydrogen Sulfide in a NAMPT/SIRT1 Dependent Manner
Recent evidence suggests that hydrogen sulfide (H(2)S) has cytoprotective and anti-aging effects. However, the mechanisms for such properties are not fully understood. Here, we show that the expression of the main H(2)S producing enzyme, CBS, and production of H(2)S are coordinately diminished in re...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061390/ https://www.ncbi.nlm.nih.gov/pubmed/27732642 http://dx.doi.org/10.1371/journal.pone.0164710 |