Cargando…
Effect of orlistat alone or in combination with Garcinia cambogia on visceral adiposity index in obese patients
AIM: The objective of this study was to estimate the effect of orlistat alone and in combination with Garcinia cambogia on visceral adiposity index (VAI) in obese patients. PATIENTS AND METHODS: A total of 99 obese male patients were recruited with aged range between 37 and 46 years. They were rando...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGEYA
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061485/ https://www.ncbi.nlm.nih.gov/pubmed/27757272 http://dx.doi.org/10.5455/jice.20160815080732 |
_version_ | 1782459612225601536 |
---|---|
author | Al-kuraishy, Hayder M. Al-Gareeb, Ali I. |
author_facet | Al-kuraishy, Hayder M. Al-Gareeb, Ali I. |
author_sort | Al-kuraishy, Hayder M. |
collection | PubMed |
description | AIM: The objective of this study was to estimate the effect of orlistat alone and in combination with Garcinia cambogia on visceral adiposity index (VAI) in obese patients. PATIENTS AND METHODS: A total of 99 obese male patients were recruited with aged range between 37 and 46 years. They were randomized into three equal groups, first group treated with orlistat 120 mg/day, second group treated with G. cambogia 166 mg/day, and third group treated with orlistat 120 mg/day plus G. cambogia 166 mg/day. The duration of the treatments was three consecutive months. Body mass index (BMI), VAI, blood pressure, blood glucose, total lipid profile, atherogenic index, and cardiac risk ratio were recorded at baseline and after 3 months. RESULTS: The treatment with G. cambogia leads to reduction in VAI P < 0.05, whereas orlistat has a beneficial effect on cardiometabolic profiles without a reduction in VAI P > 0.05. Combined therapy of G. cambogia plus orlistat showed the more significant effect in reduction of VAI P < 0.05, cardiometabolic profiles and anthropometric measures P < 0.01 compared to pretreatment period. CONCLUSION: Combination of G. cambogia with orlistat lead to more significant effect than orlistat alone in amelioration of cardiometabolic profile and VAI in obese patients. |
format | Online Article Text |
id | pubmed-5061485 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | SAGEYA |
record_format | MEDLINE/PubMed |
spelling | pubmed-50614852016-10-18 Effect of orlistat alone or in combination with Garcinia cambogia on visceral adiposity index in obese patients Al-kuraishy, Hayder M. Al-Gareeb, Ali I. J Intercult Ethnopharmacol Original Research AIM: The objective of this study was to estimate the effect of orlistat alone and in combination with Garcinia cambogia on visceral adiposity index (VAI) in obese patients. PATIENTS AND METHODS: A total of 99 obese male patients were recruited with aged range between 37 and 46 years. They were randomized into three equal groups, first group treated with orlistat 120 mg/day, second group treated with G. cambogia 166 mg/day, and third group treated with orlistat 120 mg/day plus G. cambogia 166 mg/day. The duration of the treatments was three consecutive months. Body mass index (BMI), VAI, blood pressure, blood glucose, total lipid profile, atherogenic index, and cardiac risk ratio were recorded at baseline and after 3 months. RESULTS: The treatment with G. cambogia leads to reduction in VAI P < 0.05, whereas orlistat has a beneficial effect on cardiometabolic profiles without a reduction in VAI P > 0.05. Combined therapy of G. cambogia plus orlistat showed the more significant effect in reduction of VAI P < 0.05, cardiometabolic profiles and anthropometric measures P < 0.01 compared to pretreatment period. CONCLUSION: Combination of G. cambogia with orlistat lead to more significant effect than orlistat alone in amelioration of cardiometabolic profile and VAI in obese patients. SAGEYA 2016-08-22 /pmc/articles/PMC5061485/ /pubmed/27757272 http://dx.doi.org/10.5455/jice.20160815080732 Text en Copyright: © SAGEYA http://creativecommons.org/licenses/by-nc/3.0/ This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, noncommercial use, distribution and reproduction in any medium, provided the work is properly cited. |
spellingShingle | Original Research Al-kuraishy, Hayder M. Al-Gareeb, Ali I. Effect of orlistat alone or in combination with Garcinia cambogia on visceral adiposity index in obese patients |
title | Effect of orlistat alone or in combination with Garcinia cambogia on visceral adiposity index in obese patients |
title_full | Effect of orlistat alone or in combination with Garcinia cambogia on visceral adiposity index in obese patients |
title_fullStr | Effect of orlistat alone or in combination with Garcinia cambogia on visceral adiposity index in obese patients |
title_full_unstemmed | Effect of orlistat alone or in combination with Garcinia cambogia on visceral adiposity index in obese patients |
title_short | Effect of orlistat alone or in combination with Garcinia cambogia on visceral adiposity index in obese patients |
title_sort | effect of orlistat alone or in combination with garcinia cambogia on visceral adiposity index in obese patients |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061485/ https://www.ncbi.nlm.nih.gov/pubmed/27757272 http://dx.doi.org/10.5455/jice.20160815080732 |
work_keys_str_mv | AT alkuraishyhayderm effectoforlistataloneorincombinationwithgarciniacambogiaonvisceraladiposityindexinobesepatients AT algareebalii effectoforlistataloneorincombinationwithgarciniacambogiaonvisceraladiposityindexinobesepatients |