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Effect of orlistat alone or in combination with Garcinia cambogia on visceral adiposity index in obese patients

AIM: The objective of this study was to estimate the effect of orlistat alone and in combination with Garcinia cambogia on visceral adiposity index (VAI) in obese patients. PATIENTS AND METHODS: A total of 99 obese male patients were recruited with aged range between 37 and 46 years. They were rando...

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Autores principales: Al-kuraishy, Hayder M., Al-Gareeb, Ali I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGEYA 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061485/
https://www.ncbi.nlm.nih.gov/pubmed/27757272
http://dx.doi.org/10.5455/jice.20160815080732
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author Al-kuraishy, Hayder M.
Al-Gareeb, Ali I.
author_facet Al-kuraishy, Hayder M.
Al-Gareeb, Ali I.
author_sort Al-kuraishy, Hayder M.
collection PubMed
description AIM: The objective of this study was to estimate the effect of orlistat alone and in combination with Garcinia cambogia on visceral adiposity index (VAI) in obese patients. PATIENTS AND METHODS: A total of 99 obese male patients were recruited with aged range between 37 and 46 years. They were randomized into three equal groups, first group treated with orlistat 120 mg/day, second group treated with G. cambogia 166 mg/day, and third group treated with orlistat 120 mg/day plus G. cambogia 166 mg/day. The duration of the treatments was three consecutive months. Body mass index (BMI), VAI, blood pressure, blood glucose, total lipid profile, atherogenic index, and cardiac risk ratio were recorded at baseline and after 3 months. RESULTS: The treatment with G. cambogia leads to reduction in VAI P < 0.05, whereas orlistat has a beneficial effect on cardiometabolic profiles without a reduction in VAI P > 0.05. Combined therapy of G. cambogia plus orlistat showed the more significant effect in reduction of VAI P < 0.05, cardiometabolic profiles and anthropometric measures P < 0.01 compared to pretreatment period. CONCLUSION: Combination of G. cambogia with orlistat lead to more significant effect than orlistat alone in amelioration of cardiometabolic profile and VAI in obese patients.
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spelling pubmed-50614852016-10-18 Effect of orlistat alone or in combination with Garcinia cambogia on visceral adiposity index in obese patients Al-kuraishy, Hayder M. Al-Gareeb, Ali I. J Intercult Ethnopharmacol Original Research AIM: The objective of this study was to estimate the effect of orlistat alone and in combination with Garcinia cambogia on visceral adiposity index (VAI) in obese patients. PATIENTS AND METHODS: A total of 99 obese male patients were recruited with aged range between 37 and 46 years. They were randomized into three equal groups, first group treated with orlistat 120 mg/day, second group treated with G. cambogia 166 mg/day, and third group treated with orlistat 120 mg/day plus G. cambogia 166 mg/day. The duration of the treatments was three consecutive months. Body mass index (BMI), VAI, blood pressure, blood glucose, total lipid profile, atherogenic index, and cardiac risk ratio were recorded at baseline and after 3 months. RESULTS: The treatment with G. cambogia leads to reduction in VAI P < 0.05, whereas orlistat has a beneficial effect on cardiometabolic profiles without a reduction in VAI P > 0.05. Combined therapy of G. cambogia plus orlistat showed the more significant effect in reduction of VAI P < 0.05, cardiometabolic profiles and anthropometric measures P < 0.01 compared to pretreatment period. CONCLUSION: Combination of G. cambogia with orlistat lead to more significant effect than orlistat alone in amelioration of cardiometabolic profile and VAI in obese patients. SAGEYA 2016-08-22 /pmc/articles/PMC5061485/ /pubmed/27757272 http://dx.doi.org/10.5455/jice.20160815080732 Text en Copyright: © SAGEYA http://creativecommons.org/licenses/by-nc/3.0/ This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, noncommercial use, distribution and reproduction in any medium, provided the work is properly cited.
spellingShingle Original Research
Al-kuraishy, Hayder M.
Al-Gareeb, Ali I.
Effect of orlistat alone or in combination with Garcinia cambogia on visceral adiposity index in obese patients
title Effect of orlistat alone or in combination with Garcinia cambogia on visceral adiposity index in obese patients
title_full Effect of orlistat alone or in combination with Garcinia cambogia on visceral adiposity index in obese patients
title_fullStr Effect of orlistat alone or in combination with Garcinia cambogia on visceral adiposity index in obese patients
title_full_unstemmed Effect of orlistat alone or in combination with Garcinia cambogia on visceral adiposity index in obese patients
title_short Effect of orlistat alone or in combination with Garcinia cambogia on visceral adiposity index in obese patients
title_sort effect of orlistat alone or in combination with garcinia cambogia on visceral adiposity index in obese patients
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061485/
https://www.ncbi.nlm.nih.gov/pubmed/27757272
http://dx.doi.org/10.5455/jice.20160815080732
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