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Rare Variants in Neurodegeneration Associated Genes Revealed by Targeted Panel Sequencing in a German ALS Cohort

Amyotrophic lateral sclerosis (ALS) is a progressive fatal multisystemic neurodegenerative disorder caused by preferential degeneration of upper and lower motor neurons. To further delineate the genetic architecture of the disease, we used comprehensive panel sequencing in a cohort of 80 German ALS...

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Detalles Bibliográficos
Autores principales:	Krüger, Stefanie, Battke, Florian, Sprecher, Andrea, Munz, Marita, Synofzik, Matthis, Schöls, Ludger, Gasser, Thomas, Grehl, Torsten, Prudlo, Johannes, Biskup, Saskia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061735/ https://www.ncbi.nlm.nih.gov/pubmed/27790088 http://dx.doi.org/10.3389/fnmol.2016.00092

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