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Transcription Factor Bcl11b Controls Effector and Memory CD8 T cell Fate Decision and Function during Poxvirus Infection
CD8(+) T cells play an important role in host resistance to many viral infections, but the underlying transcriptional mechanisms governing their differentiation and functionality remain poorly defined. By using a highly virulent systemic and respiratory poxvirus infection in mice, we show that the t...
Autores principales: | Abboud, Georges, Stanfield, Jessica, Tahiliani, Vikas, Desai, Pritesh, Hutchinson, Tarun E., Lorentsen, Kyle J., Cho, Jonathan J., Avram, Dorina, Salek-Ardakani, Shahram |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061747/ https://www.ncbi.nlm.nih.gov/pubmed/27790219 http://dx.doi.org/10.3389/fimmu.2016.00425 |
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