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Upstream Open Reading Frames Located in the Leader of Protein Kinase Mζ mRNA Regulate Its Translation

For protein synthesis that occurs locally in dendrites, the translational control mechanisms are much more important for neuronal functioning than the transcription levels. Here, we show that uORFs (upstream open reading frames) in the 5′ untranslated region (5′UTR) play a critical role in regulatio...

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Detalles Bibliográficos
Autores principales: Bal, Natalia V., Susorov, Denis, Chesnokova, Ekaterina, Kasianov, Artem, Mikhailova, Tatiana, Alkalaeva, Elena, Balaban, Pavel M., Kolosov, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061749/
https://www.ncbi.nlm.nih.gov/pubmed/27790092
http://dx.doi.org/10.3389/fnmol.2016.00103