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Transit times and mean ages for nonautonomous and autonomous compartmental systems
We develop a theory for transit times and mean ages for nonautonomous compartmental systems. Using the McKendrick–von Förster equation, we show that the mean ages of mass in a compartmental system satisfy a linear nonautonomous ordinary differential equation that is exponentially stable. We then def...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061853/ https://www.ncbi.nlm.nih.gov/pubmed/27038163 http://dx.doi.org/10.1007/s00285-016-0990-8 |
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author | Rasmussen, Martin Hastings, Alan Smith, Matthew J. Agusto, Folashade B. Chen-Charpentier, Benito M. Hoffman, Forrest M. Jiang, Jiang Todd-Brown, Katherine E. O. Wang, Ying Wang, Ying-Ping Luo, Yiqi |
author_facet | Rasmussen, Martin Hastings, Alan Smith, Matthew J. Agusto, Folashade B. Chen-Charpentier, Benito M. Hoffman, Forrest M. Jiang, Jiang Todd-Brown, Katherine E. O. Wang, Ying Wang, Ying-Ping Luo, Yiqi |
author_sort | Rasmussen, Martin |
collection | PubMed |
description | We develop a theory for transit times and mean ages for nonautonomous compartmental systems. Using the McKendrick–von Förster equation, we show that the mean ages of mass in a compartmental system satisfy a linear nonautonomous ordinary differential equation that is exponentially stable. We then define a nonautonomous version of transit time as the mean age of mass leaving the compartmental system at a particular time and show that our nonautonomous theory generalises the autonomous case. We apply these results to study a nine-dimensional nonautonomous compartmental system modeling the terrestrial carbon cycle, which is a modification of the Carnegie–Ames–Stanford approach model, and we demonstrate that the nonautonomous versions of transit time and mean age differ significantly from the autonomous quantities when calculated for that model. |
format | Online Article Text |
id | pubmed-5061853 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-50618532016-10-28 Transit times and mean ages for nonautonomous and autonomous compartmental systems Rasmussen, Martin Hastings, Alan Smith, Matthew J. Agusto, Folashade B. Chen-Charpentier, Benito M. Hoffman, Forrest M. Jiang, Jiang Todd-Brown, Katherine E. O. Wang, Ying Wang, Ying-Ping Luo, Yiqi J Math Biol Article We develop a theory for transit times and mean ages for nonautonomous compartmental systems. Using the McKendrick–von Förster equation, we show that the mean ages of mass in a compartmental system satisfy a linear nonautonomous ordinary differential equation that is exponentially stable. We then define a nonautonomous version of transit time as the mean age of mass leaving the compartmental system at a particular time and show that our nonautonomous theory generalises the autonomous case. We apply these results to study a nine-dimensional nonautonomous compartmental system modeling the terrestrial carbon cycle, which is a modification of the Carnegie–Ames–Stanford approach model, and we demonstrate that the nonautonomous versions of transit time and mean age differ significantly from the autonomous quantities when calculated for that model. Springer Berlin Heidelberg 2016-04-01 2016 /pmc/articles/PMC5061853/ /pubmed/27038163 http://dx.doi.org/10.1007/s00285-016-0990-8 Text en © The Author(s) 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Article Rasmussen, Martin Hastings, Alan Smith, Matthew J. Agusto, Folashade B. Chen-Charpentier, Benito M. Hoffman, Forrest M. Jiang, Jiang Todd-Brown, Katherine E. O. Wang, Ying Wang, Ying-Ping Luo, Yiqi Transit times and mean ages for nonautonomous and autonomous compartmental systems |
title | Transit times and mean ages for nonautonomous and autonomous compartmental systems |
title_full | Transit times and mean ages for nonautonomous and autonomous compartmental systems |
title_fullStr | Transit times and mean ages for nonautonomous and autonomous compartmental systems |
title_full_unstemmed | Transit times and mean ages for nonautonomous and autonomous compartmental systems |
title_short | Transit times and mean ages for nonautonomous and autonomous compartmental systems |
title_sort | transit times and mean ages for nonautonomous and autonomous compartmental systems |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061853/ https://www.ncbi.nlm.nih.gov/pubmed/27038163 http://dx.doi.org/10.1007/s00285-016-0990-8 |
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