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Abdominal Aortic Aneurysm Repair: Results from a Series of Young Patients

Objectives. To compare durability and survival after endovascular aneurysm repair (EVAR) and open repair (OR) of abdominal aortic aneurysms (AAAs) in young patients. Material and Methods. A retrospective study was conducted between 2005 and 2014 on all consecutive patients of 60 years of age or youn...

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Autores principales: Sirignano, Pasqualino, Speziale, Francesco, Montelione, Nunzio, Pranteda, Chiara, Galzerano, Giuseppe, Mansour, Wassim, Sbarigia, Enrico, Setacci, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061946/
https://www.ncbi.nlm.nih.gov/pubmed/27777952
http://dx.doi.org/10.1155/2016/7893413
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author Sirignano, Pasqualino
Speziale, Francesco
Montelione, Nunzio
Pranteda, Chiara
Galzerano, Giuseppe
Mansour, Wassim
Sbarigia, Enrico
Setacci, Carlo
author_facet Sirignano, Pasqualino
Speziale, Francesco
Montelione, Nunzio
Pranteda, Chiara
Galzerano, Giuseppe
Mansour, Wassim
Sbarigia, Enrico
Setacci, Carlo
author_sort Sirignano, Pasqualino
collection PubMed
description Objectives. To compare durability and survival after endovascular aneurysm repair (EVAR) and open repair (OR) of abdominal aortic aneurysms (AAAs) in young patients. Material and Methods. A retrospective study was conducted between 2005 and 2014 on all consecutive patients of 60 years of age or younger. Measures considered for analysis were reintervention related to AAA, laparotomy and access vessel injury during EVAR, and all-cause mortality during hospitalization and follow-up. Results. Seventy out of 119 patients were treated by OR (58.8%) and 49 (41.2%) by EVAR, 9 in off-label fashion (18.3%). Technical success was achieved in all cases. No AAA-related death was recorded. Overall in-hospital mortality was zero and the reintervention rate was 2.5% (3/119: 1/70 OR, 2/49 EVAR, p = 0.36). There is no death at 30-day or 1-year follow-up. Thirty-day reintervention rate was 1.6% (2/119; 0/70 OR, 2/49 EVAR, p = 0.16), while the 1-year rate was 2.5% (3/119; 1/70 OR, 2/49 EVAR, p = 0.36). At the mean follow-up of 56.8 ± 42.7 months, mortality and reintervention rates were 5.8% (7/119; 3/70 OR, 4/49 EVAR, p = 0.38) and 10% (12/119; 8/70 OR, 4/49 EVAR, p = 0.39), respectively. The overall reintervention rate, mortality, and freedom from adverse events did not differ between the two groups. No differences in outcome were recorded between patients treated by EVAR in on-label versus off-label fashion. Conclusion. Our (albeit limited) experience suggests that, in an unselected young patient population undergoing elective AAA repair, OR or EVAR can be performed safely with similar immediate and long term outcomes.
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spelling pubmed-50619462016-10-24 Abdominal Aortic Aneurysm Repair: Results from a Series of Young Patients Sirignano, Pasqualino Speziale, Francesco Montelione, Nunzio Pranteda, Chiara Galzerano, Giuseppe Mansour, Wassim Sbarigia, Enrico Setacci, Carlo Biomed Res Int Research Article Objectives. To compare durability and survival after endovascular aneurysm repair (EVAR) and open repair (OR) of abdominal aortic aneurysms (AAAs) in young patients. Material and Methods. A retrospective study was conducted between 2005 and 2014 on all consecutive patients of 60 years of age or younger. Measures considered for analysis were reintervention related to AAA, laparotomy and access vessel injury during EVAR, and all-cause mortality during hospitalization and follow-up. Results. Seventy out of 119 patients were treated by OR (58.8%) and 49 (41.2%) by EVAR, 9 in off-label fashion (18.3%). Technical success was achieved in all cases. No AAA-related death was recorded. Overall in-hospital mortality was zero and the reintervention rate was 2.5% (3/119: 1/70 OR, 2/49 EVAR, p = 0.36). There is no death at 30-day or 1-year follow-up. Thirty-day reintervention rate was 1.6% (2/119; 0/70 OR, 2/49 EVAR, p = 0.16), while the 1-year rate was 2.5% (3/119; 1/70 OR, 2/49 EVAR, p = 0.36). At the mean follow-up of 56.8 ± 42.7 months, mortality and reintervention rates were 5.8% (7/119; 3/70 OR, 4/49 EVAR, p = 0.38) and 10% (12/119; 8/70 OR, 4/49 EVAR, p = 0.39), respectively. The overall reintervention rate, mortality, and freedom from adverse events did not differ between the two groups. No differences in outcome were recorded between patients treated by EVAR in on-label versus off-label fashion. Conclusion. Our (albeit limited) experience suggests that, in an unselected young patient population undergoing elective AAA repair, OR or EVAR can be performed safely with similar immediate and long term outcomes. Hindawi Publishing Corporation 2016 2016-09-29 /pmc/articles/PMC5061946/ /pubmed/27777952 http://dx.doi.org/10.1155/2016/7893413 Text en Copyright © 2016 Pasqualino Sirignano et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Sirignano, Pasqualino
Speziale, Francesco
Montelione, Nunzio
Pranteda, Chiara
Galzerano, Giuseppe
Mansour, Wassim
Sbarigia, Enrico
Setacci, Carlo
Abdominal Aortic Aneurysm Repair: Results from a Series of Young Patients
title Abdominal Aortic Aneurysm Repair: Results from a Series of Young Patients
title_full Abdominal Aortic Aneurysm Repair: Results from a Series of Young Patients
title_fullStr Abdominal Aortic Aneurysm Repair: Results from a Series of Young Patients
title_full_unstemmed Abdominal Aortic Aneurysm Repair: Results from a Series of Young Patients
title_short Abdominal Aortic Aneurysm Repair: Results from a Series of Young Patients
title_sort abdominal aortic aneurysm repair: results from a series of young patients
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061946/
https://www.ncbi.nlm.nih.gov/pubmed/27777952
http://dx.doi.org/10.1155/2016/7893413
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