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The Effect of Bariatric Surgery on the Spectrum of Fatty Liver Disease

Nonalcoholic fatty liver disease is becoming one of the most common causes of liver disease in the western world. The most significant risk factors are obesity and the metabolic syndrome for which bariatric surgery has been shown to be an effective treatment. However, the effects of bariatric surger...

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Autores principales: Nostedt, Jordan J., Switzer, Noah J., Gill, Richdeep S., Dang, Jerry, Birch, Daniel W., de Gara, Christopher, Bailey, Robert J., Karmali, Shahzeer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061986/
https://www.ncbi.nlm.nih.gov/pubmed/27777925
http://dx.doi.org/10.1155/2016/2059245
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author Nostedt, Jordan J.
Switzer, Noah J.
Gill, Richdeep S.
Dang, Jerry
Birch, Daniel W.
de Gara, Christopher
Bailey, Robert J.
Karmali, Shahzeer
author_facet Nostedt, Jordan J.
Switzer, Noah J.
Gill, Richdeep S.
Dang, Jerry
Birch, Daniel W.
de Gara, Christopher
Bailey, Robert J.
Karmali, Shahzeer
author_sort Nostedt, Jordan J.
collection PubMed
description Nonalcoholic fatty liver disease is becoming one of the most common causes of liver disease in the western world. The most significant risk factors are obesity and the metabolic syndrome for which bariatric surgery has been shown to be an effective treatment. However, the effects of bariatric surgery on nonalcoholic fatty liver disease, specifically liver fibrosis and cirrhosis, are not well established. We review published bariatric surgery outcomes with respect to nonalcoholic liver disease. On the basis of this review we suggest that bariatric surgery may provide a viable treatment option for the treatment of nonalcoholic fatty liver disease, including patients with fibrosis and compensated cirrhosis, and that this topic should be a target of future investigation.
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spelling pubmed-50619862016-10-24 The Effect of Bariatric Surgery on the Spectrum of Fatty Liver Disease Nostedt, Jordan J. Switzer, Noah J. Gill, Richdeep S. Dang, Jerry Birch, Daniel W. de Gara, Christopher Bailey, Robert J. Karmali, Shahzeer Can J Gastroenterol Hepatol Review Article Nonalcoholic fatty liver disease is becoming one of the most common causes of liver disease in the western world. The most significant risk factors are obesity and the metabolic syndrome for which bariatric surgery has been shown to be an effective treatment. However, the effects of bariatric surgery on nonalcoholic fatty liver disease, specifically liver fibrosis and cirrhosis, are not well established. We review published bariatric surgery outcomes with respect to nonalcoholic liver disease. On the basis of this review we suggest that bariatric surgery may provide a viable treatment option for the treatment of nonalcoholic fatty liver disease, including patients with fibrosis and compensated cirrhosis, and that this topic should be a target of future investigation. Hindawi Publishing Corporation 2016 2016-09-29 /pmc/articles/PMC5061986/ /pubmed/27777925 http://dx.doi.org/10.1155/2016/2059245 Text en Copyright © 2016 Jordan J. Nostedt et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Nostedt, Jordan J.
Switzer, Noah J.
Gill, Richdeep S.
Dang, Jerry
Birch, Daniel W.
de Gara, Christopher
Bailey, Robert J.
Karmali, Shahzeer
The Effect of Bariatric Surgery on the Spectrum of Fatty Liver Disease
title The Effect of Bariatric Surgery on the Spectrum of Fatty Liver Disease
title_full The Effect of Bariatric Surgery on the Spectrum of Fatty Liver Disease
title_fullStr The Effect of Bariatric Surgery on the Spectrum of Fatty Liver Disease
title_full_unstemmed The Effect of Bariatric Surgery on the Spectrum of Fatty Liver Disease
title_short The Effect of Bariatric Surgery on the Spectrum of Fatty Liver Disease
title_sort effect of bariatric surgery on the spectrum of fatty liver disease
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061986/
https://www.ncbi.nlm.nih.gov/pubmed/27777925
http://dx.doi.org/10.1155/2016/2059245
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