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Physical Properties and Effect in a Battery of Safety Pharmacology Models for Three Structurally Distinct Enteric Polymers Employed as Spray-Dried Dispersion Carriers

Establishing a wide therapeutic index (TI) for pre-clinical safety is important during lead optimization (LO) in research, prior to clinical development, although is often limited by a molecules physiochemical characteristics. Recent advances in the application of the innovative vibrating mesh spray...

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Detalles Bibliográficos
Autores principales:	Fryer, Ryan M., Patel, Mita, Zhang, Xiaomei, Baum-Kroker, Katja S., Muthukumarana, Akalushi, Linehan, Brian, Tseng, Yin-Chao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062032/ https://www.ncbi.nlm.nih.gov/pubmed/27790142 http://dx.doi.org/10.3389/fphar.2016.00368

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