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Short-term Effects of Outdoor Air Pollution on Lung Function among Female Non-smokers in China

Short-term exposures to outdoor air pollutants have been associated with lower lung function, but the results are inconsistence. The effects of different pollutant levels on lung function changes are still unclear. We quantified the effects of outdoor air pollution exposure (NO(2), PM(10), O(3), and...

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Autores principales: Zhou, Yun, Liu, Yuewei, Song, Yuanchao, Xie, Jungang, Cui, Xiuqing, Zhang, Bing, Shi, Tingming, Yuan, Jing, Chen, Weihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062123/
https://www.ncbi.nlm.nih.gov/pubmed/27734830
http://dx.doi.org/10.1038/srep34947
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author Zhou, Yun
Liu, Yuewei
Song, Yuanchao
Xie, Jungang
Cui, Xiuqing
Zhang, Bing
Shi, Tingming
Yuan, Jing
Chen, Weihong
author_facet Zhou, Yun
Liu, Yuewei
Song, Yuanchao
Xie, Jungang
Cui, Xiuqing
Zhang, Bing
Shi, Tingming
Yuan, Jing
Chen, Weihong
author_sort Zhou, Yun
collection PubMed
description Short-term exposures to outdoor air pollutants have been associated with lower lung function, but the results are inconsistence. The effects of different pollutant levels on lung function changes are still unclear. We quantified the effects of outdoor air pollution exposure (NO(2), PM(10), O(3), and PM(2.5)) on lung function among 1,694 female non-smokers from the Wuhan-Zhuhai Cohort in China by using linear mixed model. We further investigated the associations in the two cities with different air quality levels separately to quantify the effects of different pollutant level exposure on lung function. We found the moving averages of NO(2), PM(10), and PM(2.5) concentrations were significantly associated with reduced FVC. In city at high pollutant level, the moving average of NO(2), PM(10), O(3), and PM(2.5) exposures were significantly associated with both FVC and FEV(1) reductions. In the low-level air pollution city, PM(10) (Lag03-Lag05) and O(3) concentrations (Lag01-Lag03) were significantly associated with reduced FVC, while PM(10) (Lag03-Lag05), O(3) (Lag0-Lag03), and PM(2.5) (Lag04-Lag06) exposure were significantly associated with reduced FEV(1). Our results suggest that outdoor air pollution is associated with short-term adverse effects on lung function among female non-smokers. The adverse effects may persist for longer durations within 7 days at higher air pollutant levels.
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spelling pubmed-50621232016-10-24 Short-term Effects of Outdoor Air Pollution on Lung Function among Female Non-smokers in China Zhou, Yun Liu, Yuewei Song, Yuanchao Xie, Jungang Cui, Xiuqing Zhang, Bing Shi, Tingming Yuan, Jing Chen, Weihong Sci Rep Article Short-term exposures to outdoor air pollutants have been associated with lower lung function, but the results are inconsistence. The effects of different pollutant levels on lung function changes are still unclear. We quantified the effects of outdoor air pollution exposure (NO(2), PM(10), O(3), and PM(2.5)) on lung function among 1,694 female non-smokers from the Wuhan-Zhuhai Cohort in China by using linear mixed model. We further investigated the associations in the two cities with different air quality levels separately to quantify the effects of different pollutant level exposure on lung function. We found the moving averages of NO(2), PM(10), and PM(2.5) concentrations were significantly associated with reduced FVC. In city at high pollutant level, the moving average of NO(2), PM(10), O(3), and PM(2.5) exposures were significantly associated with both FVC and FEV(1) reductions. In the low-level air pollution city, PM(10) (Lag03-Lag05) and O(3) concentrations (Lag01-Lag03) were significantly associated with reduced FVC, while PM(10) (Lag03-Lag05), O(3) (Lag0-Lag03), and PM(2.5) (Lag04-Lag06) exposure were significantly associated with reduced FEV(1). Our results suggest that outdoor air pollution is associated with short-term adverse effects on lung function among female non-smokers. The adverse effects may persist for longer durations within 7 days at higher air pollutant levels. Nature Publishing Group 2016-10-13 /pmc/articles/PMC5062123/ /pubmed/27734830 http://dx.doi.org/10.1038/srep34947 Text en Copyright © 2016, The Author(s) http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Zhou, Yun
Liu, Yuewei
Song, Yuanchao
Xie, Jungang
Cui, Xiuqing
Zhang, Bing
Shi, Tingming
Yuan, Jing
Chen, Weihong
Short-term Effects of Outdoor Air Pollution on Lung Function among Female Non-smokers in China
title Short-term Effects of Outdoor Air Pollution on Lung Function among Female Non-smokers in China
title_full Short-term Effects of Outdoor Air Pollution on Lung Function among Female Non-smokers in China
title_fullStr Short-term Effects of Outdoor Air Pollution on Lung Function among Female Non-smokers in China
title_full_unstemmed Short-term Effects of Outdoor Air Pollution on Lung Function among Female Non-smokers in China
title_short Short-term Effects of Outdoor Air Pollution on Lung Function among Female Non-smokers in China
title_sort short-term effects of outdoor air pollution on lung function among female non-smokers in china
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062123/
https://www.ncbi.nlm.nih.gov/pubmed/27734830
http://dx.doi.org/10.1038/srep34947
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