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Lysozyme and bilirubin bind to ACE and regulate its conformation and shedding

Angiotensin I-converting enzyme (ACE) hydrolyzes numerous peptides and is a critical participant in blood pressure regulation and vascular remodeling. Elevated tissue ACE levels are associated with increased risk for cardiovascular and respiratory disorders. Blood ACE concentrations are determined b...

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Detalles Bibliográficos
Autores principales: Danilov, Sergei M., Lünsdorf, Heinrich, Akinbi, Henry T., Nesterovitch, Andrew B., Epshtein, Yuliya, Letsiou, Eleftheria, Kryukova, Olga V., Piegeler, Tobias, Golukhova, Elena Z., Schwartz, David E., Dull, Randal O., Minshall, Richard D., Kost, Olga A., Garcia, Joe G. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062130/
https://www.ncbi.nlm.nih.gov/pubmed/27734897
http://dx.doi.org/10.1038/srep34913