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A comparative study of Sterofundin and Ringer lactate based infusion protocol in scoliosis correction surgery

BACKGROUND: A major change in anesthesia practice as regards to intraoperative infusion therapy is the present requirement. Switching over to balanced fluids can substantially decrease the incidence of lactic acidosis and hyperchloremic acidosis. The deleterious effects of unbalanced fluids are more...

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Autores principales: Sharma, Ashima, Yadav, Monu, Kumar, B. Rajesh, Lakshman, P. Sai, Iyenger, Raju, Ramchandran, Gopinath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062242/
https://www.ncbi.nlm.nih.gov/pubmed/27746547
http://dx.doi.org/10.4103/0259-1162.181425
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author Sharma, Ashima
Yadav, Monu
Kumar, B. Rajesh
Lakshman, P. Sai
Iyenger, Raju
Ramchandran, Gopinath
author_facet Sharma, Ashima
Yadav, Monu
Kumar, B. Rajesh
Lakshman, P. Sai
Iyenger, Raju
Ramchandran, Gopinath
author_sort Sharma, Ashima
collection PubMed
description BACKGROUND: A major change in anesthesia practice as regards to intraoperative infusion therapy is the present requirement. Switching over to balanced fluids can substantially decrease the incidence of lactic acidosis and hyperchloremic acidosis. The deleterious effects of unbalanced fluids are more recognizable during major surgeries. We prospectively studied the influence of Sterofundin (SF) and Ringer lactate (RL) on acid–base changes, hemodynamics, and readiness for extubation during scoliosis surgery. SUBJECTS AND METHODS: Thirty consecutive children posted for scoliosis surgery were randomized to receive either RL (n = 15) or SF (n = 15) as intraoperative fluid at 10 mg/kg/h. Fluid boluses were added according to the study fluid algorithm. Arterial blood was sampled and analyzed at hourly intervals during surgery. Red blood cell transfusion was guided by hematocrit below 27. Patients were followed for 24 h postoperatively in the Intensive Care Unit. RESULTS: There was no statistically significant difference in the volume of infused fluid (2400 ± 512 ml in Group RL and 2200 ± 640 ml in Group SF. There were no significant changes in pH of patients infused with SF. Statistically, significant higher lactate levels were seen in RL-infused group. The strong ion difference was decreased in both groups, but it normalized earlier with SF. CONCLUSIONS: SF-infused patients had nonremarkable changes in acid–base physiology in scoliosis surgery.
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spelling pubmed-50622422016-10-14 A comparative study of Sterofundin and Ringer lactate based infusion protocol in scoliosis correction surgery Sharma, Ashima Yadav, Monu Kumar, B. Rajesh Lakshman, P. Sai Iyenger, Raju Ramchandran, Gopinath Anesth Essays Res Original Article BACKGROUND: A major change in anesthesia practice as regards to intraoperative infusion therapy is the present requirement. Switching over to balanced fluids can substantially decrease the incidence of lactic acidosis and hyperchloremic acidosis. The deleterious effects of unbalanced fluids are more recognizable during major surgeries. We prospectively studied the influence of Sterofundin (SF) and Ringer lactate (RL) on acid–base changes, hemodynamics, and readiness for extubation during scoliosis surgery. SUBJECTS AND METHODS: Thirty consecutive children posted for scoliosis surgery were randomized to receive either RL (n = 15) or SF (n = 15) as intraoperative fluid at 10 mg/kg/h. Fluid boluses were added according to the study fluid algorithm. Arterial blood was sampled and analyzed at hourly intervals during surgery. Red blood cell transfusion was guided by hematocrit below 27. Patients were followed for 24 h postoperatively in the Intensive Care Unit. RESULTS: There was no statistically significant difference in the volume of infused fluid (2400 ± 512 ml in Group RL and 2200 ± 640 ml in Group SF. There were no significant changes in pH of patients infused with SF. Statistically, significant higher lactate levels were seen in RL-infused group. The strong ion difference was decreased in both groups, but it normalized earlier with SF. CONCLUSIONS: SF-infused patients had nonremarkable changes in acid–base physiology in scoliosis surgery. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC5062242/ /pubmed/27746547 http://dx.doi.org/10.4103/0259-1162.181425 Text en Copyright: © Anesthesia: Essays and Researches http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Sharma, Ashima
Yadav, Monu
Kumar, B. Rajesh
Lakshman, P. Sai
Iyenger, Raju
Ramchandran, Gopinath
A comparative study of Sterofundin and Ringer lactate based infusion protocol in scoliosis correction surgery
title A comparative study of Sterofundin and Ringer lactate based infusion protocol in scoliosis correction surgery
title_full A comparative study of Sterofundin and Ringer lactate based infusion protocol in scoliosis correction surgery
title_fullStr A comparative study of Sterofundin and Ringer lactate based infusion protocol in scoliosis correction surgery
title_full_unstemmed A comparative study of Sterofundin and Ringer lactate based infusion protocol in scoliosis correction surgery
title_short A comparative study of Sterofundin and Ringer lactate based infusion protocol in scoliosis correction surgery
title_sort comparative study of sterofundin and ringer lactate based infusion protocol in scoliosis correction surgery
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062242/
https://www.ncbi.nlm.nih.gov/pubmed/27746547
http://dx.doi.org/10.4103/0259-1162.181425
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