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Tissue-specific and convergent metabolic transformation of cancer correlates with metastatic potential and patient survival

Cancer cells undergo a multifaceted rewiring of cellular metabolism to support their biosynthetic needs. Although the major determinants of this metabolic transformation have been elucidated, their broad biological implications and clinical relevance are unclear. Here we systematically analyse the e...

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Detalles Bibliográficos
Autores principales: Gaude, Edoardo, Frezza, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062467/
https://www.ncbi.nlm.nih.gov/pubmed/27721378
http://dx.doi.org/10.1038/ncomms13041