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Coordinated integrin activation by actin-dependent force during T-cell migration

For a cell to move forward it must convert chemical energy into mechanical propulsion. Force produced by actin polymerization can generate traction across the plasma membrane by transmission through integrins to their ligands. However, the role this force plays in integrin activation is unknown. Her...

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Detalles Bibliográficos
Autores principales: Nordenfelt, Pontus, Elliott, Hunter L., Springer, Timothy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062559/
https://www.ncbi.nlm.nih.gov/pubmed/27721490
http://dx.doi.org/10.1038/ncomms13119

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