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Coordinated integrin activation by actin-dependent force during T-cell migration
For a cell to move forward it must convert chemical energy into mechanical propulsion. Force produced by actin polymerization can generate traction across the plasma membrane by transmission through integrins to their ligands. However, the role this force plays in integrin activation is unknown. Her...
Autores principales: | Nordenfelt, Pontus, Elliott, Hunter L., Springer, Timothy A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062559/ https://www.ncbi.nlm.nih.gov/pubmed/27721490 http://dx.doi.org/10.1038/ncomms13119 |
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