Familial Occurrence of Enteric Muco-Submucosal Elongated Polyp

We report 2 cases of enteric muco-submucosal elongated polyps (EMSEPs) that presented with gastrointestinal bleeding. The 2 patients are siblings. They both had a history of percutaneous coronary intervention for coronary artery disease and were on dual antiplatelet therapy. They underwent endoscopi...

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Detalles Bibliográficos
Autores principales: Shimamura, Yuto, Nakamura, Kenji, Okamoto, Takeshi, Imamura, Noriatsu, Ishii, Naoki, Fujita, Yoshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American College of Gastroenterology 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062661/
https://www.ncbi.nlm.nih.gov/pubmed/27807549
http://dx.doi.org/10.14309/crj.2016.60
Descripción
Sumario:We report 2 cases of enteric muco-submucosal elongated polyps (EMSEPs) that presented with gastrointestinal bleeding. The 2 patients are siblings. They both had a history of percutaneous coronary intervention for coronary artery disease and were on dual antiplatelet therapy. They underwent endoscopic resection of the polyps, which displayed identical endoscopic and histological features compatible with EMSEP. This is the first report of familial occurrence of EMSEP, suggesting possible genetic involvement. It is also important to note that the use of antiplatelet agents appears to be a predisposing factor for gastrointestinal bleeding from EMSEP.

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