Cardiovascular metabolic risk factors and glomerular filtration rate: a rural Chinese population study

METHODS: A total of 2426 study subjects from rural China aged 35 years and above (934 men and 1492 women) were enrolled in a cross-sectional survey. The eGFR calculation was based on the Modification of Diet in Renal Disease (MDRD) equation. The strength of the association between cardiovascular met...

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Autores principales: Zheng, Wei, Qian, Geng, Hao, Wenjun, Geng, Xiaodong, Hong, Quan, Cai, Guangyan, Chen, Xiangmei, Wu, Di
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062868/
https://www.ncbi.nlm.nih.gov/pubmed/27733200
http://dx.doi.org/10.1186/s12944-016-0346-9
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author Zheng, Wei
Qian, Geng
Hao, Wenjun
Geng, Xiaodong
Hong, Quan
Cai, Guangyan
Chen, Xiangmei
Wu, Di
author_facet Zheng, Wei
Qian, Geng
Hao, Wenjun
Geng, Xiaodong
Hong, Quan
Cai, Guangyan
Chen, Xiangmei
Wu, Di
author_sort Zheng, Wei
collection PubMed
description METHODS: A total of 2426 study subjects from rural China aged 35 years and above (934 men and 1492 women) were enrolled in a cross-sectional survey. The eGFR calculation was based on the Modification of Diet in Renal Disease (MDRD) equation. The strength of the association between cardiovascular metabolic risk factors and eGFR was analyzed using a linear regression model. RESULTS: Cardiovascular metabolic risk factors, including age, body weight, waist circumference, fasting plasma glucose (FPG), creatinine (Cr), high-density lipoprotein-cholesterol (HDL-C), total cholesterol (TC), triglyceride (TG), systolic pressure, and diastolic pressure, were associated with eGFR. Additionally, the eGFR level gradually decreased and showed a linear trend with the increase in metabolic syndrome risk factors. CONCLUSION: Metabolic risk factors are correlated with a reduction in renal function and CKD.
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spelling pubmed-50628682016-10-17 Cardiovascular metabolic risk factors and glomerular filtration rate: a rural Chinese population study Zheng, Wei Qian, Geng Hao, Wenjun Geng, Xiaodong Hong, Quan Cai, Guangyan Chen, Xiangmei Wu, Di Lipids Health Dis Research METHODS: A total of 2426 study subjects from rural China aged 35 years and above (934 men and 1492 women) were enrolled in a cross-sectional survey. The eGFR calculation was based on the Modification of Diet in Renal Disease (MDRD) equation. The strength of the association between cardiovascular metabolic risk factors and eGFR was analyzed using a linear regression model. RESULTS: Cardiovascular metabolic risk factors, including age, body weight, waist circumference, fasting plasma glucose (FPG), creatinine (Cr), high-density lipoprotein-cholesterol (HDL-C), total cholesterol (TC), triglyceride (TG), systolic pressure, and diastolic pressure, were associated with eGFR. Additionally, the eGFR level gradually decreased and showed a linear trend with the increase in metabolic syndrome risk factors. CONCLUSION: Metabolic risk factors are correlated with a reduction in renal function and CKD. BioMed Central 2016-10-12 /pmc/articles/PMC5062868/ /pubmed/27733200 http://dx.doi.org/10.1186/s12944-016-0346-9 Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Zheng, Wei
Qian, Geng
Hao, Wenjun
Geng, Xiaodong
Hong, Quan
Cai, Guangyan
Chen, Xiangmei
Wu, Di
Cardiovascular metabolic risk factors and glomerular filtration rate: a rural Chinese population study
title Cardiovascular metabolic risk factors and glomerular filtration rate: a rural Chinese population study
title_full Cardiovascular metabolic risk factors and glomerular filtration rate: a rural Chinese population study
title_fullStr Cardiovascular metabolic risk factors and glomerular filtration rate: a rural Chinese population study
title_full_unstemmed Cardiovascular metabolic risk factors and glomerular filtration rate: a rural Chinese population study
title_short Cardiovascular metabolic risk factors and glomerular filtration rate: a rural Chinese population study
title_sort cardiovascular metabolic risk factors and glomerular filtration rate: a rural chinese population study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062868/
https://www.ncbi.nlm.nih.gov/pubmed/27733200
http://dx.doi.org/10.1186/s12944-016-0346-9
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