Cargando…
Persistent neuroinflammation and cognitive impairment in a rat model of acute diisopropylfluorophosphate intoxication
BACKGROUND: Acute intoxication with organophosphorus (OP) cholinesterase inhibitors can trigger convulsions that progress to life-threatening status epilepticus. Survivors face long-term morbidity including mild-to-severe decline in memory. It is posited that neuroinflammation plays a key role in th...
Autores principales: | Flannery, Brenna M., Bruun, Donald A., Rowland, Douglas J., Banks, Christopher N., Austin, Adam T., Kukis, David L., Li, Yonggang, Ford, Byron D., Tancredi, Daniel J., Silverman, Jill L., Cherry, Simon R., Lein, Pamela J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062885/ https://www.ncbi.nlm.nih.gov/pubmed/27733171 http://dx.doi.org/10.1186/s12974-016-0744-y |
Ejemplares similares
-
Persistent neuropathology and behavioral deficits in a mouse model of status epilepticus induced by acute intoxication with diisopropylfluorophosphate
por: Calsbeek, Jonas J., et al.
Publicado: (2021) -
Sex-specific acute and chronic neurotoxicity of acute diisopropylfluorophosphate (DFP)-intoxication in juvenile Sprague-Dawley rats
por: González, Eduardo A., et al.
Publicado: (2021) -
Allopregnanolone and perampanel as adjuncts to midazolam for treating diisopropylfluorophosphate‐induced status epilepticus in rats
por: Dhir, Ashish, et al.
Publicado: (2020) -
Gut dysbiosis following organophosphate, diisopropylfluorophosphate (DFP), intoxication and saracatinib oral administration
por: Gage, Meghan, et al.
Publicado: (2022) -
Neuroinflammation as a Therapeutic Target for Mitigating the Long-Term Consequences of Acute Organophosphate Intoxication
por: Andrew, Peter M., et al.
Publicado: (2021)